Lysoril, ma ọ bụ lisinopril dihydrate, bụ ọgwụ mbadamba iji mee ka mbelata ọbara mgbe ọ bilitere (ọbara mgbali elu).
International Nonproprietary Aha
Lisinopril.
Lysoril, ma ọ bụ lisinopril dihydrate, bụ ọgwụ a na-eji belata ọbara mgbali mgbe ọ biliri.
ATX
Ọgwụ nwere Lodinopril itinye C09AA03.
Ha weputara udi ya na ihe mebere ya
Odikwa n ’ụdị dị ka mbadamba ụrọ nwere pesenti 2.5; 5; 10 ma ọ bụ 20 mg ọ bụla.
Dịka akụkụ nke ọgwụ ahụ, ihe kachasị arụ ọrụ bụ lisinopril dihydrate. Ihe ndi ozo bu mannitol, calcium hydrogen phosphate dihydrate, magnesium stearate, ọka ọka, E172, ma obu uro iron iron.
Mbadamba nkume ndị ahụ dị gburugburu, biconvex, pink dị na agba.
Omume ọgwụ
Na-ezo aka ọgwụ ndị na-emetụta steeti usoro ahụ. Ọgwụ ahụ na-egbochi ntụgharị nke angiotensin 1 na angiotensin 2, nwere vasoconstrictor mmetụta ma gbochie guzobe adrenal aldosterone. Na-ebelata oke mgbochi vaskụla, ọbara mgbali, nrụgide n'ime akpa ume akpa ume, ibugo. Ọ na-eme ka mmepụta obi ọwụwa na-abawanye nnabata myocardial na ndị nwere nkụda obi.
Mbelata ọbara mgbali pụtara otu awa mgbe ị theụsịrị ọgwụ.
Site na iji Lizoril ruo ogologo oge, a na-ahụ mbelata ọbara mgbali myocardial na mgbidi akwara nke ụdị resistive. Mbelata ọbara mgbali pụtara otu awa mgbe ị theụsịrị ọgwụ. A na - enweta nsonaazụ kasịnụ mgbe awa 6 gachara, ogologo oge nke mmetụta ahụ bụ ihe dịka otu ụbọchị. Ọ dabere na ntụtụ nke ihe ahụ, steeti anụ ahụ, ọrụ nke akụrụ na umeji.
Mlọ ọgwụ
A na-ahụta nlebara anya kachasị elu 7 awa mgbe nchịkwa gasịrị. Ego ole dị n’aru ahụ bụ 25%, opekata mpe bụ 6%, ma kacha karịa bụ 60%. N'ime ndị ọrịa nwere nkụda obi, a na-ebelata bioav adị site na 15-20%.
N'ime mkpụrụ mmamịrị ahụ agbanweghị. Iri nri anaghị emetụta mmịpụta. Ogo nke banye n’ime oghere mgbochi ụbụrụ na ọbara.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ n'ọnọdụ ndị a:
- obere oge ọgwụgwọ nke nnukwu myocardial infarction (ruo izu isii);
- ọbara mgbali;
- ọrịa mamịrị nephropathy (Mbelata protein na mmamịrị n'ime ndị ọrịa nwere ọrịa shuga n'ọbara dị elu ma bulie elu).
Ihe ngbanwe
Amachibidoro iweghara ma ọ bụrụ na amata:
- Hypersensitivity na mpaghara ọ bụla nke ọgwụ ma ọ bụ ọgwụ sitere na otu otu ọgwụ ọgwụ.
- Edema na akụkọ banyere ụdị angioneurotic.
- Hemodynamics na-ejighị n'aka na nnukwu nsogbu myocardial infarction.
- Ọnụnọ nke ọkwa dị elu nke creatinine (karịa 220 μmol / l).
A na - enye ọgwụ ogwu maka ndị ọrịa na - awa ọria ya na ụmụ nwanyị n'oge ime na lactation.
Jiri nlezianya
Edere ọgwụ ahụ nke ọma na ọnụnọ nke stenosis akwara ma ọ bụ valves - mitral na aortic, akụrụ na imeju, akwara obi na-egbu egbu, ọkwa potassium dị elu, mgbe a mechara ya arụ ọrụ na mmerụ ahụ, yana ọrịa mellitus, ọrịa ọbara, mmeghachi omume nfụkasị.
Etu esi ewere Lizoril?
N'ime oge 1 kwa ụbọchị. A họrọ usoro ị drugụ ọgwụ ahụ n'ọnọdụ ọ bụla n'otu n'otu. Ọtụtụ mgbe, ọgwụgwọ na-amalite site na 10 mg. Mgbe ahụ gbanwee ya ma ọ dị mkpa.
Na-arịa ọrịa shuga
N'ime ndị ọrịa nwere ụdị shuga nke 2, usoro mbụ nke ọgwụ ahụ bụ 10 mg 1 oge kwa ụbọchị.
Nsonaazụ Lizoril
Ogwu nwere ike ibute nsonaazụ, ụfọdụ n’ime ha na-apụ naanị ha, ndị ọzọ chọrọ ọgwụgwọ.
Ọkpụkpụ afọ
Afọ kpọnwụrụ na ọgbụgbọ, ọgbụgbọ, mgbu afọ, afọ ọsịsa, afọ ntachi, mbufụt nke pancreas, belatara agụụ, ọrịa imeju, ụdọ, cholestasis, angioedema nke eriri afọ, ọrịa ịba ọcha n'anya.
Ahụhụ Hematopoietic
Mbelata hematocrit na haemoglobin, mgbochi nke ụmị ọkpụkpụ ọbara ọbara, mgbanwe n'ọdịdị ọbara ụbụrụ, thrombocytopenia, agranulocytosis, neutropenia, leukopenia, ọrịa autoimmune, lymphadenopathy, hemolytic type anemia.
Sistemụ akwara Central
Mmetụta ọhụhụ, nkụda mmụọ, akụrụngwa akwara, isi isi, enweghị ntị, tinnitus, mmetụta na uto, nsogbu ihi ụra, mgbanwe ọnọdụ, isi ọwụwa na ọgbụgba, nsogbu na nhazi.
Site na sistem iku ume
Ọrịa elu akụkụ akụkụ okuku ume na akpa ume, ụkwara, rhinitis, bronchitis na spasm, mkpụmkpụ nke iku ume, mbufụt nke paranasal sinuses, mmeghachi ahụ nfụkasị, oyi baa.
Site na usoro akwara obi
Ihe omume Orthostatic (hypotension), ọnya afọ, infarction myocardial, ọrịa Raynaud, palpitations, cardiogenic ujo, cardiac blockade 1-3 ogo, mgbali elu na capillaries pulmonary.
Ahụhụ
Mmeghachi omume enwere site na anụ ahụ yana akwa oyi akwa dị ka rashes, itching, inwekwu mmụọ - angioedema, ọria anụ ahụ ihu na olu, hyperemia, urticaria, eosinophilia.
Mmeghachi omume enwere ike site na anụ ahụ na akwa oyi akwa, dịka rashes, itching.
Mmetụta ikike ịchịkwa usoro
N'ihi na mgbe ị na-ewere Lizoril, enwere ike ịnwe nkụda mmụọ, ọdịda ya, mgbe ị na - arụ ọrụ na usoro mgbagwoju anya na ịnya ụgbọ ala, ekwesịrị ịkpachara anya ma ọ bụ, ọ bụrụ na ọ ga - ekwe omume, ịhapụ ụdị ọrụ a.
Ntụziaka pụrụ iche
Usoro ị drugụ ọgwụ ahụ nwere ike ịdị iche iche, dabere na afọ, ọnọdụ arụ ọrụ nke akụkụ ahụ (obi, umeji, akụrụ, akwara ọbara).
Site na ọrịa obi, ọrịa obi, nkụchi obi, ọnya afọ, nwere ike ịmalite. Ya mere, achọrọ mmezi onyunyo na nyocha oge niile maka ọnọdụ ndị ọrịa.
Jiri na agadi
Imezi usoro onunu ogwu achoro.
Inye umuaka
A na-egbochi ọgwụ a na ụmụaka, n'ihi na Enwebeghị ọmụmụ ọmụmụ ụlọ ọgwụ.
Jiri n'oge ime na lactation
Emebela.
Ngwa maka ọrụ ezughi oke ọrụ
Mgbe ị na-edepụta ego nye ndị ọrịa nwere akụrụ gbasara akwara, usoro ọgwụgwọ usoro a ga-ekpebi site na ọkwa nke creatinine n'ọbara yana nzaghachi anụ ahụ na usoro ọgwụgwọ.
Mgbe ị na-edepụta ego nye ndị ọrịa nwere akụrụ gbasara akwara, usoro ọgwụgwọ usoro a ga-ekpebi site na ọkwa nke creatinine n'ọbara yana nzaghachi anụ ahụ na usoro ọgwụgwọ.
Na ọgbụgba akwara gbasara akụrụngwa ọbara, ọgwụ nwere ike ime ka mmụba urea na ọkwa creatinine, ọbara ọgbụgba gbasara akụrụ, ma ọ bụ oke hypotension na nsogbu na-akawanye njọ gbasara akụrụ. Site na anamnesis dị otú a, ọ bara uru iji nlezianya depụta ọgwụ dials ma lelee usoro ịtelyụ ọgwụ ọ bụla, ịchịkwa ọkwa nke potassium, creatinine na urea.
Site na mmepe nke infarction myocardial na ndị ọrịa nwere ọrụ akwara nsogbu, Lizoril bụ contraindicated.
Jiri maka ọrụ imeju na-arụ ọrụ
Ojiji nke ị rarelyụ ọgwụ nwere ike ibute nsogbu nke sistemụ ịba ọcha n'anya. Agbanyeghị, mgbe ụfọdụ enwere umeji, jaundice, hyperbilirubinemia / hyperbilibinemia, na mmụba na ọrụ hepatic transaminase nwere ike ịmalite. N'okwu a, ịkagbu ọgwụ ahụ.
Dodoụbiga mmanya ókè
A na-egosiputa mgbaàmà n'ụdị mbelata ọbara ọgbụgba, ahaghị n ’elektrolytes, ọdịda akụrụ, tachy ma ọ bụ bradycardia, ọgbụgbọ, ụkwara, nchekasị. A na-eme ọgwụgwọ Symptomatic.
Dizzness bụ otu n'ime ihe ịrịba ama nke ịdoụbiga mmanya ókè.
Ọ ga-adị mkpa ịsụ nsị, ime ka ọgbụgbọ, nye sorbents ma ọ bụ diaals. N'ọnọdụ siri ike, a na-enye ọgwụ ọgwụ infusion, a na-edozi catecholamines.
Mmekọrịta na ọgwụ ndị ọzọ
Diuretics: enwere mmụba na mbelata ọbara mgbali elu.
Lithium: A naghị atụ aro iji ihe mkpuchi oriri. To Toụ mmanya na-aba ụba. Ọ bụrụ na ọ dị mkpa, chịkwaa ọkwa lithium dị n’ọbara.
NSAIDs: nsonaazụ nke ndị na - egbochi ACE na-ebelata, enwere ịrị elu na potassium n'ime ọbara, na-eme ka ohere nke akụrụ mebie.
Ọgwụ maka ọrịa shuga: mbelata nke glucose ọbara, ihe ize ndụ nke hypoglycemia na coma na-abawanye.
Estrogens: jigide mmiri n'ime ahụ, yabụ ha nwere ike belata nsonaazụ nke ọgwụ.
Ọgwụ ndị ọzọ maka mbenata ọbara ọgbụgba na ọgwụ antidepressants: ihe ọghọm nke mbelata ọbara mgbali elu.
Mmanya ndakọrịta
Na-efu efu. Ikekwe mmụba na mmetụta dị ala nke lisinopril, ike ọgwụgwụ hypotension nwere ike ịmalite.
Analogs
Mmekorita nke Lysoril bu Lisinoton, Lisinopril-Teva, Irumed, Lisinopril, Diroton.
Ahịa ọgwụ na-ahapụ okwu
Okwu di nkpa.
Enwere m ike ịzụta na ndenye ọgwụ?
Ee e.
Ọnụahịa
Ọnụ ego nke ngwugwu 1 dị iche dabere na ọnụ ọgụgụ mbadamba na usoro onunu ogwu. Ya mere, ọnụahịa maka mbadamba 28 nke 5 mg nke ihe ahụ bụ 106 rubles.
Ọnọdụ nchekwa maka ọgwụ
Ọ na-atụ aro ịchekwa ngwaahịa ahụ n'ebe ebe ụmụaka agaghị eru. Oge okpomoku ekwesịghị ịfe 25 Celsius.
Bọchị mmebi
Odibeghi afọ 3.
Emeputa
Companylọ ọrụ ndị India bụ Ipka Limited Laboratories.
A na-egbochi ọgwụ a na ụmụaka, n'ihi na Enwebeghị ọmụmụ ọmụmụ ụlọ ọgwụ.
Nyocha
Oksana, onye gbara afọ 53, Minsk: “Edebere Lizoril afọ 3 gara aga n'ihi ọbara mgbali elu. Ọnwụ mmiri a mechara bụrụ nke a na-ahụkarị. Ọ bụrụgodi na ọkwa mgbali bilitere, ọ baghị oke (tupu 180). M kwụsịrị ịtụ egwu ọrịa strok. ọ dịghị ngosipụta bilitere. "
Maxim, onye dị afọ 28, Krymsk: “Enwere m ọbara mgbali elu kemgbe m bụ nwata. Agbalịrị m ọtụtụ ọgwụ n'oge a, mana mgbali elu na-adịkarị afọ abụọ gara aga, dọkịta ahụ depụtara ụzọ Lizoril .. Ihe mgbaàmà ugbu a anaghị enwe nsogbu, nke kachasị mkpa, enweghị ọdịda dị nkọ. mgbali, na tupu nke a, m na-enwekarị nsụhọ n'ihi nke a. Ọbara na-achịkwa m afọ ojuju. "
Anna, dị afọ 58, St. Petersburg: “Anọwo m ọgwụ ahụ ihe dị ka ọnwa isii (site na njikwa creatinine) Ọkwa nrụgide alaghachila nkịtị. Ihe isi ike bụ na enwere m ọrịa nephropathy megide mmalite nke ụdị ọrịa shuga 2 nke ọrịa mellitus, ya mere m na-ewerekarị ule na oge ụfọdụ dọkịta. na-agbanwe usoro onunu ogwu a. Mana ogwu a masiri m n'ihi na enweghi uto obula, o dikwa ya nma karie ya otu ugboro kwa ubochi.