Etu esi eji ọgwụ ahụ Tritace Plus?

Irè nke Tritace Plus sitere na nsonaazụ nke ramipril na hydrochlorothiazide. Ihe abuo ndi a na - egbochi mmeghari nke angiotensin nke mbu nke uzo nke anakpo angiotensin II, si otua nweta ihe anakpo antihypertensive. N'okwu a, ọgwụ ahụ adịkarịghị ka etinyere ya ọgwụ na omume ọgwụgwọ dị ka monotherapy. Ndị ọrịa na - enweta ọgwụ ume dị ka akụkụ nke usoro ọgwụgwọ siri ike nke ọbara mgbali elu iji wee nwee ọkwa mgbali elu.

International Nonproprietary Aha

Hydrochlorothiazide + Ramipril.

ATX

C09BA05.

Irè nke Tritace Plus sitere na nsonaazụ nke ramipril na hydrochlorothiazide.

Ha weputara udi ya na ihe mebere ya

Ọgwụ ahụ dị n'ụdị mbadamba. Otu mbadamba 1 na - agwakọta agwakọta abụọ na - arụ ọrụ - ramipril na hydrochlorothiazide.

Iji meziwanye ọgwụ ọgwụ, a na-eji ihe ndị ọzọ eme ihe:

• sodium stearyl fumarate;
• ihe eji eme ka ihe ndi ozo di na ntaneti, nke na-enye mbadamba nkume ure ndi mmadu dika ndi mmadu n’oru ya;
• ọka gelatinized;
• microcrystalline cellulose;
• hypromellose.

Mbadamba mbadamba ụrọ, na eriri nkewa abụọ.

Ọ dịkarịghị ọgwụ edere ya ka ọ rụọ ọrụ ọgwụgwọ dị ka monotherapy.

Omume ọgwụ

Tritace na - ejikọ angiotensin na - agbanwe enzyme (ACE) inhibitor - ramipril, na thiazide diuretic hydrochlorothiazide. Nchikota nke ihe ndi di ike nwere mmetụta antihypertensive siri ike. Ihe mgbochi ACE na-egbochi ịmepụta angiotensin II, nke dị mkpa iji belata akwara anụ ahụ na-eme ka akwara ike nke endothelium.

Ramipril na - egbochi ihe omume vasoconstrictor ma gbochie mmebi nke bradykinin, ihe maka mmụba nke akwara ọbara. Hydrochlorothiazide na-akwalite vasodilation, n'ihi nke arịa ndị ahụ na-agbasawanye. Ọ dị mkpa idobe oke ọbara na-agagharị iji gbochie mmepe nke bradycardia na hypotension.

A na-ahụkarị ọgwụgwọ kachasị elu 3-6 awa mgbe ngwa a wee dịgide otu ụbọchị. Mmetụta diuretic nke thiazide diuretic dịruru ruo awa 6-12.

Mlọ ọgwụ

Ramipril na hydrochlorothiazide na-abanye ngwa ngwa na jojunum proximal, site na ebe ha na-agbasa n'ime mgbasa usoro. Bioavailability hydrochlorothiazide bụ 70%. N'ime ọbara, kemịkal abụọ ahụ na-erute itinye uche n'ihe kachasị n'ime awa 2-4. Ramipril nwere oke nke jikọtara ya na protein ndị dị na plasma - 73%, ebe naanị 40% nke hydrochlorothiazide bụ ụlọ nwere albumin.

Ndụ ọkara nke ihe abụọ ahụ ruru elekere 5-6. Ramipril bụ 60% pịrị apị na mmamịrị. Hydrochlorothiazide na-ahapụ ahụ ahụ n'ụdị ya mbụ site na 95% site na akụrụ ya n'ime awa iri abụọ na anọ.

Ihe ngosi maka ojiji

Ọ dị mkpa iji ọgwụ ahụ belata ọbara mgbali elu.

Ọ dị mkpa iji ọgwụ ahụ belata ọbara mgbali elu.

Ihe ngbanwe

A na - eji ọgwụ ahụ eme ihe na ndị mmadụ:

• hypersensitivity na hydrochlorothiazide, ramipril na ihe ndi ozo nke Tritace;
• ntụgharị aka na mmepe nke edebi Quincke;
• nnukwu nshịkọ akụrụngwa;
• mgbanwe na plasma electrolytes: potassium, magnesium, calcium;
• ọrịa imeju siri ike;
• nnukwu ike ọgwụgwụ hypotension.

Jiri nlezianya

Ọ dị mkpa ịchịkwa ọdịmma mmadụ niile n'oge usoro ọgwụgwọ ọgwụ na ọnụnọ ọrịa ndị a:

• oke obi ike;
• ọgba aghara na ventricle aka ekpe, nke mgbanwe mgbanwe hypertrophic mara;
• stenosis nke isi, arịa ụbụrụ, akwara ozi ma ọ bụ akwara akwara;
• nsogbu nke metabolism mmiri-electrolyte;
• na mwepụ nke creatinine nke 30-60 ml / min;
• oge ndozi mgbe akụrụ gbasasịrị;
• ọrịa imeju
• mmebi nke anụ ahụ njikọ - scleroderma, lupus erythematosus;
• mmegbu nke ụbụrụ ụbụrụ.

Ọrịa kwesịrị ibu ụzọ chịkọta mmiri nnu.

Ntuchi ogwu eji eme ihe bu ezughi oke gbasara akwara.

N'ime ọrịa ọrịa imeju siri ike, a machibidoro ọgwụ a.

Ekwesịrị iji ịkpachara anya na nkụchi obi.

Uzo esi ewere Tritace Plus

Edeghị ọgwụ ahụ ka ọ bụrụ ọgwụ izizi maka mbufụt. Mbadamba nkume ndi a bu ka eji eme ihe. Medicationakingara ọgwụ n'ụtụtụ ka akwadoro. Ọ bụ ọkachamara n’ọgwụ na-ekpebi usoro ọgwụgwọ ahụ dabere n’ihe ngosipụta nke ọbara mgbali (BP) na ogo ọbara mgbali elu.

Standardkpụrụ ọkọlọtọ na mbido ọgwụgwọ ọgwụ bụ 2.5 mg nke ramipril na 12.5 mg nke hydrochlorothiazide. Site na nnabata ziri ezi, iji mee ka mmetụta hypotensive dị ukwuu, enwere ike ịba ụba usoro onwa mgbe izu 2-3 gachara.

Na-arịa ọrịa shuga

Ọgwụ nwere ike ibute hypoglycemia na iji ọgwụ hypoglycemic ọgwụ ma ọ bụ insulin, ya mere, n'oge a na-eji ọgwụ ọgwụ antihypertensive, ọ dị mkpa iji dozie usoro ọgwụ ọgwụ antidiabetic. Ndị ọrịa nwere ọrịa shuga kwesịrị ilebara ọkwa glucose ọbara ha anya.

Nsonaazụ Tritace Plus

N'ọnọdụ ụfọdụ, ịgwọ Tritace na-ekwesịghị ekwesị na-eduga ike ọgwụgwụ na ahụ ọkụ.

Ọkpụkpụ afọ

A na-enwe nsogbu ngwangwa nke mmepe nke mbufụt nke akpụkpọ ahụ mucous, ọdịdị nke gingivitis, refomes na vomiting, na afọ ntachi. Ikekwe mmepe nke gastritis, ahụ erughị ala na afọ.

Site na ọrịa eriri afọ, gastritis nwere ike ịmalite dịka mmetụta dị n'akụkụ.

Ahụhụ Hematopoietic

Site na mbelata ụdọ ụmị ọkpụkpụ, ọnụ ọgụgụ sel nke akpụ akpụ na-agbada.

Sistemụ akwara Central

Site na mwepu nke mmụọ-mmetụta uche, onye ọrịa nwere nkụda mmụọ, nchekasị, na nsogbu ihi ụra. N’ibi ndabere nke nkụda mmụọ nke sistem akwara, enwere mwepu nke uche na oghere, isi ọwụwa, mmetụ ọkụ, mfu ma ọ bụ ụtọ iwe.

Site na usoro urinary

Ikekwe, mmụba nke mmamịrị ewepụtara na mmepe nke akụrụ oke.

Site na sistem iku ume

N'ọnọdụ ka ukwuu, n'ihi mmụba nke ọkwa bradykinin, ụkwara pụrụ ịrịa, n'ụfọdụ ndị ọrịa - mkpọchi imi na mbufụt nke sinuses.

Na anụahụ

E nwere nsogbu nke ịmalite ọrịa angioedema, nke nwere ike ibute asphyxia n'ọnọdụ ụfọdụ. Arịa ọrịa psoriasis, mmụba ịba ụba, rashes, itching na erythema nke etiologies dị iche iche ga-ekwe omume.

N'ihi ị theụ ọgwụ, erythema nke etiologies dị iche iche nwere ike ịmalite.

Site na usoro mkpụrụ ndụ ihe nketa

N'ime ụmụ nwoke, mbelata nke mmụba na ịrị elu na glands mammary ga-ekwe omume.

Site na usoro akwara obi

Eleghi anya mbelata nke ọbara mgbali, thrombosis n'ihi akpịrị mmiri, stenosis nke arịa ndị bụ isi, igbochi mgbasa ọbara, ọnya mgbidi vaskụla na ọrịa Raynaud.

Usoro endocrine

O kwere omume ịmụba ụba homonụ nke antidiuretic.

N'akuku nke imeju na akụkụ biliary

N'ọnọdụ ndị pụrụ iche, mbufụt cytolytic nke imeju na-amalite site na nsonaazụ na-egbu egbu ga-ekwe omume. Enwere mmụba nke ọkwa bilirubin n'ọbara na nrịanrịa nke cholecystitis na-enweghị atụ.

Ahụhụ

A na-ahụta nsogbu ọrịa Allergic site n’ile anya na mmeghachi omume anụ ahụ.

A na-ahụta nsogbu ọrịa Allergic site n’ile anya na mmeghachi omume anụ ahụ.

Site na usoro akwara na uru ahụ

Mmadu nwere ike inwe ihe mgbu na adighi ike n’aru ahu.

Site n'akụkụ nke metabolism

N'ọnọdụ ndị pụrụ iche, enwere mbelata glucose anụ ahụ, n'ihi nke shuga ọbara na-abawanye. Imebi metabolism nke izugbe, ihe urea dị na plasma ọbara na-abawanye, gout na-akpalite ma na anorexia na-eto. N'ọnọdụ ndị a na-adịghị ahụkebe, hypokalemia na metabolic acidosis na-eto.

Site na usoro ahụ ji alụso ọrịa ọgụ

Ikekwe mmepe nke mmeghachi omume anaphylactic n'ihe metụtara mmụba na ụzọ nke ọgwụ mgbochi antinuclear. Tritace na-anabata nnabata nwere ike ịkpalite ihu ihu, obere eriri afọ, aka na asụsụ.

Mmetụta ikike ịchịkwa usoro

N'ihi nsonaazụ enwere ike ịhụ anya na enweghị uche, onye ọrịa ga-akpachara anya mgbe ọ na-anya ngwaọrụ ndị siri ike ma ọ bụ ụgbọ ala ndị chọrọ nnukwu mmeghachi omume psychomotor na ịbawanye ụba.

N'ihi nsonaazụ anya nke anya na enweghị uche, onye ọrịa kwesịrị ịkpachara anya mgbe ọ na-anya ngwaọrụ ndị siri ike ma ọ bụ ụgbọ.

Ntụziaka pụrụ iche

Tupu usoro ọgwụgwọ ịwa ahụ ezubere, ọ dị mkpa ịdọ onye dọkịta na-awa ahụ na onye na-ahụ maka ọgwụ na-ahụ maka ọrụ ọgwụgwọ banyere otu onye na - egbochi ACE. Nke a dị mkpa iji gbochie mbelata ọbara mgbali n'oge ịwa ahụ.

Jiri n'oge ime na lactation

N'ihi nsonaazụ teratogenic na fetotoxic, ọgwụ edeghị ọgwụ maka ụmụ nwanyị dị ime. Enwere ihe ize ndụ nke intrauterine ara n'ime nwa ebu n’afọ.

N'oge ọgwụgwọ, ị ga-akwụsị inye ara.

Oge ntanetị Tritace Plus maka ụmụaka

N'ihi ụkọ data na nsonaazụ Tritace n'ahụ ahụ mmadụ n'oge mmepe ahụ, a na-amịpụta ọgwụ ahụ na ụmụaka na-erubeghị afọ 18.

Jiri na agadi

Agaghị eme mgbanwe maka ndị agadi na usoro ọgwụgwọ ahụ.

Agaghị eme mgbanwe maka ndị agadi na usoro ọgwụgwọ ahụ.

Ngwa maka ọrụ ezughi oke ọrụ

Ndị ọrịa na-arịa ọrịa akụrụ dị obere ruo na-aga aga kwesịrị ịtụle ọrụ akụkụ ahụ n'oge ọgwụgwọ.

Jiri maka ọrụ imeju na-arụ ọrụ

Amachibidoro ọgwụ a maka ndị nwere ọrịa imeju.

Nmefere nke Tritace Plus

Onyinye omuma a nke ihe riri oke gosiputara onwe ya na mmetuta nke onye nzuzu, a na-ahuta ya na ngosiputa ndi a.

• polyuria, nke n'ime ndị ọrịa nwere ezigbo ọrịa prostate adenoma ma ọ bụ mmamịrị ndị ọzọ nwere nsogbu na-akpalite mmepe nke mgbagide nke urination site na ịnọpụ ọnya;
• bradycardia, arrhythmia;
• vasodilation nke onwe;
• mmebi nke metabolism mmiri-electrolyte;
• ọgba aghara na mfu nke mmụọ na mmụba nke ụdi;
• ogwe akwara;
• eriri afọ ezigbo akwara dysfunction.

Ọ bụrụ na ihe na-erughị nkeji 30-90 agafeela kemgbe eburu ogwu ahụ, mgbe ahụ ọ dị mkpa ka onye ahụ metụtara megharia ọgbụgbọ na imechi afọ ya. Mgbe usoro ahụ gachara, onye ọrịa ahụ kwesịrị iwere adsorbent iji belata nnabata nke ihe ndị dị ike. Na bradycardia siri ike, ọ dị mkpa iwebata 1-2 mg nke adrenaline intravenously ma ọ bụ guzobe pacemaker nwa oge. Ọ bụrụ na ị doụbiga ya ókè, ọ dị mkpa ijikwa ọkwa ọbara ọbara na ọ̀tụ̀tụ̀ ọbara ji erugharị n'oge ọgwụgwọ.

An overụbiga ọgwụ ókè, akwara nwere ike ịpụta.

Mmekọrịta na ọgwụ ndị ọzọ

Site na nhazi nke Tritace na thiazides n'otu oge, nchịkọta nke cholesterol n'ọbara ọbara nwere ike ịba ụba.

Ngwakọta ndị amachibidoro

Achọpụtara ọgwụ ọgwụ na iji ya mee ihe yiri nke aliskiren na angiotensin II antagonists. N'ọnọdụ ikpeazu, a na-ekekọta ihe nchịkwa na ndị ọrịa nwere polyneuropathy mamịrị. Achọghị Aliskiren ka ọria ya na akwara gbasara oke akwara.

Ngwakọta anaghị atụ aro

Ekwesighi inye ọgwụ ndị ejikọtara ọnụ na ọgwụ ịra ụra, ọgwụ lithium, tacrolimus nwere sulfamethoxazole.

Mgwakọta chọrọ ịkpachara anya

Ọ dị mkpa iji chekwaa usoro nchekwa n'otu oge atọrọ:

• ọgwụ mgbochi tricyclic;
• ọgwụ mgbochi mbu;
• mgbochi barbituric acid;
• ego maka anesthesia izugbe;
• ngwọta sodium chloride;
• ọgwụ diuretic;
• vasopressor sympathomimetics;
• allopurinol, ndị ọrụ immunomodulatory, glucocorticosteroids, cytostatics;
• estramustine, heparin, vildagliptin;
• ndị ọrịa hypoglycemic.

N'oge usoro ọgwụgwọ, ekwesighi iji nduku nwere mmanụ ethanol na ngwaahịa mmanya.

Ọ dị mkpa ịkwụsị ị etụ ethanol.

Mmanya ndakọrịta

N'oge usoro ọgwụgwọ, ekwesighi iji nduku nwere mmanụ ethanol na ngwaahịa mmanya. Mgbe ị na-ewere Tritace na ethanol na myirịta, enwere ihe ọghọm nke ida.

Analogs

A na-eme ntụgharị ahụ na ọgwụ ọzọ na - egbochi ọgwụ mgbochi ọnụ, na - ahụ maka onye dọkịta, onye nwere ike ịdepụta otu n'ime ọgwụ ndị na - esote dịka ọgwụ nnọchi:

• Hartil-D;
• Amprilan NL;
• Amprilan ND;
• Wazolong H;
• Ramazid H.

Analogs nwere ike inweta karịa na ọnụahịa ọnụahịa - 210-358 rubles.

Ahịa ọgwụ na-ahapụ okwu

Erere maka ahụike.

Enwere m ike ịzụta na ndenye ọgwụ

Ọgwụ ahụ nwere ike ibute hyperatara orthostatic ma ọ bụrụ na-ejighị ya. Maka nchekwa nke ndị ọrịa n'ụlọ ahịa ọgwụ, enwere ike iji ọgwụ ndenye ọgwụ zụta ọgwụ.

Ọnụahịa na Tritac Plus

Ọnụ ego maka mbadamba 5 mg bụ 954-1212 rubles, yana usoro nke 10 mg - 1537 rubles.

Ọnọdụ nchekwa maka ọgwụ

A na-ahapụ mbadamba nkume ka ọ nwee ike idobe ya na ọnọdụ okpomọkụ nke + 8 ... + 30 Celsius C n'ebe dịpụrụ adịpụ maka ọrụ nke ìhè anyanwụ.

Bọchị mmebi

Afọ 3

Emeputa

Sanofi Aventis, Italy.

Nyocha Tritac

Ntụle dị mma banyere ọgwụ ahụ na-egosi na ọgwụ ahụ eguzobewo onwe ya na ahịa ọgwụ.

Ndi dibia

Svetlana Gorbacheva, dibia bekee, Ryazan

Ọ bụ ihe dị na hydrochlorothiazide nwere. Chemical ahụ na - akwalite mmetụta antihypertensive. M na-enye ndị ọrịa ọrịa ọgwụ naanị naanị mgbali elu akwara maka otu ọgwụ kwa ụbọchị. Ogologo oge ọgwụgwọ bụ onye ọ bụla maka onye ọrịa ọ bụla. Enweghị mmetụta ọ bụla a hụrụ. A naghị anabata ndị nwere nnukwu nsogbu gbasara akụrụ.

Ndị ọrịa

Alexey Lebedev, 30 afọ, Yaroslavl

Nwanyị ahụ malitere igosipụta ọbara mgbali elu n'afọ ndụ. N'ihi ọbara mgbali elu, ekwesịrị ị drugsụ ọgwụ antihypertensive kwa ụbọchị. N'ụbọchị ole na ole gara aga, Tritace bụ aka enyemaka ogologo oge. Mbadamba ụrọ ahụ na-eme ka ọbara mgbali dị mma nke ọma ma anaghị akpata nsonaazụ. Site n'iji ogologo oge, ịkwesịrị ịla ezumike ma ọ bụ mee ka usoro ahụ dịkwuo elu, n'ihi na anụ ahụ ga-akwụsị ịchọpụta mbadamba mbadamba. Naanị ihe ndọghachi azụ bụ uto ilu.

Elena Shashkina, 42 afọ, Vladivostok

A kpọpụrụ Tritace na nne ya mgbe ọrịa strok kpatara n'ihi ọbara mgbali elu. Ọgwụ nyere aka - mama ahụ mara mma, ọnọdụ mgbali ike akwụsịla. Mama m na-ewere obere opekempe ka ọgwụ ahụ wee dị ogologo. Dabere na ndụmọdụ dọkịta ahụ, mgbe ọnwa ole ọ bụla na-anabata ya, ọ kwụsịrị iji ya maka izu 1-2. Nke a dị mkpa ka enweghị mmetụta na ihe iri mmadụ ahụ.