Ọgwụ Gluconorm maka ndị ọrịa mamịrị - ntuziaka maka ojiji

Gluconorm bụ otu ọgwụ a toụrụ iji gwọọ ụdị ọrịa shuga 2. Ọgwụ nwere mmetụta hypoglycemic.

Gluconorm dị n'ụdị mbadamba ma bu n'obi maka nchịkwa ọnụ.

Ozi izugbe, ihe mejupụtara na ụdị ịtọhapụ

Gluconorm bụ ọgwụ ọgwụ hypoglycemic emepụtara na India. Na mgbakwunye na mmetụta hypoglycemic, ọgwụ na-enyere aka belata mkpokọ cholesterol n'ọbara onye ọrịa.

A na-ahapụ ya inyefe ego ego dị ka ọgwụ nke ndị ọkachamara na-esite na ya si dị. A na-eji ọgwụ ahụ eme ihe maka afọ 3 site na ụbọchị nke emepụtara ya.

Ọ dị mkpa iji lelee ọnọdụ nchekwa ọgwụ a. A na-echekwa ya n'ebe gbara ọchịchịrị na-enweghị ohere ụmụaka nwere. Okpukpo nchekwa kachasi nma bu 20-23⁰K.

Na mgbakwunye, a na-emepụta Gluconorm nke nwere mkpụrụ osisi breeki n'ụdị nke herbal tii, nke abụghị ọgwụ, kama a na-ewere ya dị ka ihe ọ -ụ sugarụ shuga.

Isi ihe dị na ọgwụ ahụ bụ Metformin Hydrochloride na Glibenclamide. Ọdịnaya nke ihe mbụ n’ime 1 mbadamba bụ 400 mg, nke abụọ - 2.5 mg. Cellulose na microcrystals na silloon silikon dioxide dị ka ihe ndị ọzọ na ngwakọta nke nkwadebe ahụ. A na-ahụkwa ihe dị iche iche nke croscarmellose, diethyl phthalate na glycerol.

N'ime ihe ndị ọzọ dị na ọgwụ ahụ, steeti sodium carboxymethyl, magnesium stearate na cellacephate. N'ọtụtụ ebe, ọgwụ talc na stachi ọka na gelatin dị na nhazi nke ọgwụ.

Otu mkpọ mbadamba nwere blisters 1-4. N'ime ọnya nwere ike ịbụ mbadamba ọgwụ ọgwụ 10, 20, 30. Mbadamba ọgwụ a na-acha ọcha ma nwee ọdịdị biconvex. N'oge ezumike, mbadamba nkume ahụ nwere ike ịnwe obere isi awọ.

Gluconorm blueberry tii nwere ihe ndị dị n’ime mbadamba ụrọ. A na-eme ya site na mkpịsị ahịhịa sitere n'okike wee resị ya n'ụdị akpa tii. Ezubere usoro mbanye ahụ izu atọ.

Pharmacology na pharmacokinetics

Gluconorm nwere ihe abụọ dị mkpa: Glibenclamide na Metformin. Ihe abuo a na - aru ​​oru na ihe ndi ozo na - emekota aru oru.

Glibenclamide bụ usoro nke abụọ na-abanye na usoro sulfonylurea. N'ihi ọrụ ya, a na-akpali insulin n'ahụ, ọ na-enwekwa insulin ike nke ukwuu na-abawanye na mkpụrụ ndụ ndị chọrọ.

Glibenclamide na-akwalite mwepụta insulin na-arụ ọrụ ma na-akwalite mmetụta ya na nnabata glucose site na imeju, yana uru ahụ. N'okpuru ihe eji eme ihe, usoro nke kewara abụba na anụ ahụ adipose na-akwụsịlata.

Metformin bụ ihe biguanide. N'ihi ihe ọ na-eme, a na-ebelata mkpụkọ glucose na ọbara onye ọrịa, a na -eme ka mmụba glucose dị n ’elu anụ ahụ.

Ihe a na –eme ka mmata nke uche nke cholesterol dị mma. N'ihi ọrụ Metformin, ịmịkọrọ carbohydrates na afọ na eriri afọ na-ebelata. Ihe a na egbochi oke imeju glucose n'ime imeju.

Glibenclamide na Metformin, nke bụ akụkụ nke ọgwụ ahụ, nwere ọgwụ ọgwụ dị iche iche.

Ntinye nke glibenclamide mgbe amachara site na afọ na eriri afọ ruru 84%. Oke ịta nke ihe nwere ike iru na otu elekere ma ọ bụ abụọ. Ihe a na-emekọrịta ihe nke ọma na protein protein. Ọnụego ya bụ 95%. Ọkara dịkarịsịrị ọkara bụ 3 awa, kacha kacha bụ awa iri na isii. Ihe akụrụ ahụ dọbara akụkụ ahụ akụkụ ya ụfọdụ, eriri afọ ya.

Otutu bioavailability nke Metformin abụghị ihe karịrị 60%. Iri nri na –ebelata ike nke metformin. Ihe a na -eme n’afọ efu n’afọ na-adọta nke ọma n’afọ na eriri afọ.

N'adịghị ka Glibenclamide, ọ nwere ihe mgbochi dị ala na protein protein. Ọ bụ ya mere akụrụ. 30% nke ihe nwere ike ịnọ na feces nke onye ọrịa. Iwepu ọkara ndụ na-ewe awa iri na abụọ.

Ihe ngosi na contraindications

Isi ihe na-egosi ị takingụ ọgwụ a bụ ọnụnọ nke ọrịa shuga II na onye ọrịa. Ọzọkwa, edere ọgwụ ahụ na enweghị mmetụta dị mma nke ọgwụgwọ na nri, mmega ahụ na ọgwụgwọ dabere na ị takingụ Metformin na Glibenclamide.

Emekwara ka ọgwụ a pụta ìhè maka ndị ọrịa nwere shuga ọbara nkịtị ma kwụsie ike, mana ndị nwere mkpa iji dochie Glibenclamide na Metformin.

Ọnụ ọgụgụ dị ukwuu nke contraindications bụ njirimara ọgwụ:

• afọ imeju;
• mbelata nke ịta suga ọbara (hypoglycemia);
• oke uche n'ihe ndị dị na ọgwụ ahụ;
• ụdị m ọrịa shuga mellitus;
• mmanya na-egbu egbu;
• ime
• arụrụ ọrụ na-arụ ọrụ n’iru ndị ọrịa n’ihi ọrịa, ujo;
• ketoacidosis;
• ihe miconazole;
• ọnụnọ nke ọkụ na ahụ;
• nkụchi obi;
• inye ara;
• ọrịa dị iche iche;
• ọrịa shuga;
• ọdịda odida;
• infarction myocardial;
• rụrụ ọrụ ịwa ahụ;
• lactic acidosis;
• nsị mmanya;
• okpu iku ume;
• precca ọrịa shuga;
• Ọrịa porphyrin.

Ntụziaka maka ojiji

A na-eji ọgwụ a ọgwụ. Maka onye ọrịa ọ bụla, usoro ọgwụ Gluconorm dị iche iche ehibere.

Iji ọgwụgwọ ya na-ewere ọnọdụ n'ọtụtụ nkebi. Na mbido mbụ, a na-ewere mbadamba ọgwụ 1 kwa ụbọchị. Ọgwụgwọ dịka atụmatụ a siri dị ụbọchị 14. N’ọdịnihu, a na-edobe ọgwụ ahụ n’ichebara ọnọdụ onye ọrịa na ndị gosipụtara shuga n’ọbara ya echiche.

Mgbe ị na-edochi usoro ọgwụgwọ, onye ọrịa ahụ na-ewere mbadamba 1-2 nke ọgwụ. Oke kachasị ga-ekwe omume n'oge a bụ mbadamba ise.

Ndị Ọrịa na Nduzi Pụrụ Iche

Amachibidoro ọgwụ a maka ụmụ nwanyị dị ime. Ọ bụ ihe anakwereghị ị takeụ ọgwụ ahụ n'oge ị na-eme atụmatụ ịtụrụ ime.

Ekwesịrị ka a glyconorm site na ịmị ụmụ nwanyị, ebe Metformin na-abanye ike n'ime mmiri ara ma nwee ike imetụta ahụike nke nwa amụrụ ọhụrụ. N'ọnọdụ ndị a, akwadoro ọgwụ maka iji ọgwụ insulin dochie anya.

A naghị akwado ọgwụ ahụ maka ndị ọrịa meworo agadi nke afọ ha karịrị afọ 60. Na mgbakwunye na nnukwu ibu, Gluconorm nwere ike ibute lactic acidosis na ụdị ndị a.

Ọgwụ chọrọ nlekọta nlezianya site n'aka ndị ọrịa na-arịa:

• ụkpa adrenal;
• ahụ ọkụ;
• ọrịa thyroid.

Maka ọgwụ, a na-enye ọtụtụ ntuziaka pụrụ iche:

• n'oge ọgwụgwọ, ịdị na-enyocha ọkwa glucose ọbara mgbe niile dị mkpa na afọ na-enweghị isi na mgbe nri gasịrị;
• amachibidoro ị jointụ ọgwụ na mmanya.
• ọ dị mkpa iji ọgwụ insulin dochie ọgwụ ma ọ bụrụ na onye ọrịa nwere mmerụ ahụ, ọrịa, ahụ ọkụ, ọkụ, ọrụ gara aga;
• 2bọchị 2 tupu iwebata ihe na-emepụta rediopaque nke nwere ayodiin n’ime ahụ onye ọrịa, ọ dị mkpa ịkwụsị ị theụ ọgwụ ahụ (mgbe ụbọchị 2 gasịrị, ịmaliteghachi ọgwụ ahụ);
• nchịkwa nkwonkwo nke Gluconorm na ethanol na-akpasu hypoglycemia, ọ na-adịkwa n’oge a na-ebu ọnụ ma na-a drugsụ ọgwụ mgbochi mkpali nke ụdị steroid;
• ọgwụ a na-emetụta ike onye ọrịa ịnya ụgbọ ala (must ga-ezere iji ụgbọ ala na-eme njem n'oge ị withgwọ ọgwụ).

Mmetụta akụkụ na ị andụbiga mmanya ókè

Ka usoro ị withụ ọgwụ gwọọ ya, onye ọrịa nwere ike ịnwe nsonaazụ ndị ọzọ:

• ọbara ọgbụgba dị ala (hypoglycemia) belatara;
• agụụ riri;
• leukopenia;
• anya ntughari;
• itching na anụ ahụ;
• lactic acidosis;
• ọgbụgba na vomiting;
• thrombocytopenia;
• ike ọgwụgwụ
• urticaria;
• ọria iku ume yana ihu na-arịa ihu na tachycardia, dị ka nzaghachi maka ị simụ mmanya n'otu oge;
• mgbu afọ
• anaemia
• isi ọwụwa;
• ahụ ọkụ;
• mbelata nke uche;
• ọdịdị nke protein dị na mmamịrị;
• jaundice
• ịba ọcha n'anya na-adịghị ahụkebe.

Enwere ike igosipụta njupụta nke ọgwụ ahụ dị ka:

• lactic acidosis;
• hypoglycemia.

Losic acidosis na-akpalite ihe mgbu, ọgbụgbọ, na mgbu afọ. Mgbaàmà nke ọrịa ahụ chọrọ ịkwụsị ọgwụ ozugbo na itinye onye ọrịa n'ụlọ ọgwụ. Nhọrọ ọgwụgwọ kachasị dị irè bụ nhicha ọbara ọbara (hemodialysis).

Glibenclamide nwere ike ibute ọrịa hypoglycemia n'ime onye ọrịa. Ọ bụrụ ụra, isi ọwụwa. Ọzọkwa kwukwara: pallor, nhazi nhazi, ọsụsọ, enweghị mmụọ.

A na-ewepụ hypoglycemia n'ụdị dị nro ma na-agafe agafe site na ịgwọta ndị ọrịa shuga. N'ọnọdụ ndị siri ike, a na-etinye ya ọgwụ nwere 40% glucose. Okwu mmeghe a ga –eme ma intravenial intramuscularly.

Njikọ Ọgwụ na Analogs

Ihe ndị a na-eso njikọta ọgwụ ndị ọzọ bụ njiri mara ọgwụ ahụ:

• ethanol na gluconorm ọnụ na-akpalite lactic acidosis;
• ọgwụ cationic (Vancomycin, Morphine, Quinine, Amiloride) na-emewanye mkpokọta Metformin site na 60%;
• barbiturates, dị ka clonidine, furosemide,Danazole, Morphine, nnu nke lithium, estrogens, Baclafen, Glucagon, homonụ thyroid, Phenytoin, Epinephrine, Chlortalidone, nicotinic acid, Triamteren, Acetazolamide na-ebelata oke ọgwụgwọ nke ọgwụ ahụ;
• Cimetidine, ndị ọrụ hypoglycemic, Tetracycline, Ethionamide, Guanethidine, fibrates, antifungals, enalapril, Theophylline, Cyclophosphamide, salicitates, Pentoxifylline, Pyridoxine, reserpine, anabolic steroids na-eme ka ọgwụ antidiabetic ghara ịdị;
• calcium chloride tinyere ammonium chloride, yana oke ascorbic acid, na-eme ka ọgwụ dịkwuo mma;
• Furosemide na-emetụta ntinye uche nke metformin na ntuziaka nke mmụba ya site na 22%.

Anafọdụ n'ime ọgwụ analogues bụ isi:

• Ike nke Metglib;
• Glibomet;
• Glucophage;
• Ndị Glucovans;
• Metglib;
• Bagomet Plus.

Ihe vidio gbasara iwetulata shuga ọbara n'ụdị shuga abụọ:

Echiche onye ọrịa

Ọtụtụ nyocha banyere ọrịa mamịrị banyere ọgwụ Gluconorm nwere mmetụta dị mma maka ị theụ ọgwụ, etu ọ dị, ekwuputara nsonaazụ ndị ọzọ, n'etiti ọgbụgbọ na isi ọwụwa na-enwekarị, nke a na-ewepụ site na ndozi dose.

Ọgwụ dị mma, ọ na-ebelata shuga nke ọma. N'ụzọ dị ịtụnanya, ahụghị m mmetụta ọ bụla na-adịkarị ka ọ na-ede banyere ya. Dị ọnụ ọnụ ọnụahịa. Ana m enye iwu Gluconorm na usoro na - aga n'ihu.

Svetlana, 60 afọ

Anọ m na-arịa ụdị ọrịa shuga 2 ruo ọtụtụ afọ. Dọkịta na-aga ahụ nyere ọgwụ Gluconorm. Na mbido, enwere nsonaazụ: mgbe mgbe ọ na-arịa ọrịa, enwere nkụwa. Ma n ’ọdịniihu, anyị dozigharịrị ọnya, ma ihe niile gafere. Ngwá ọrụ dị irè ma ọ bụrụ na ijikọta nri ya na nri.

Tatyana, 51 afọ

Gluconorm bụ ihe a pụrụ ịdabere na ya kpamkpam. N'ọnọdụ nke m, enyere m aka imeziwanye ibu ahụ. Ọgwụ na-ebelata agụụ. N'ime minuses, aga m akọwapụta nsonaazụ ndị ọzọ. E nwere ọtụtụ n’ime ha. N’otu oge, isi m rịawara ọrịa.

Eve, gbara afọ 43

Ọ bụghị oge dị anya gara aga, onye ọrịa endocrinologist mere nchọpụta nchọpụta na-adịghị mma - ụdị shuga 2. Edere glucose na-edozi shuga ọbara. N'ozuzu obi ụtọ na ọgwụgwọ. Na nnukwu shuga, ọgwụ nwere ike belata ọkwa ya ruo 6 mmol / L. Enwere ụfọdụ mmetụta dị n'akụkụ, mana a na-ewepụ ya. Iri nri.

Anatoly, 55 afọ

Ọnụ ego gluconorm na mpaghara dị iche iche nke mba ahụ nwere ọdịiche. Ọnụ ego ná mba ahụ bụ 212 rubles. Ọnụ ego ọgwụ ahụ bụ 130-294 rubles.