Usoro nri na ịmịkọrọ nri si na nri na - apụta site n'ihe ọ toụ pancụ pancreatic mepụtara site na pancreas na-abanye na eriri afọ. Ihe nzuzo a na-enwe n’ahụ nwere ihe enzymes nke na-ebute ụzọ n’agwu nri.
Usoro nke imeputa, ụdị na ọrụ
A na - eme pancreas bụ ngwakọta nke nzuzo, n'ihi na ọ na - eme ọ bụghị naanị enzymes diges, kamakwa homonụ - insulin, glucagon na lipocaine. Insulin na glucagon na-edozi metabolism nke metabolism, yana lipocaine nwere ihe homonụ na-ahụ maka sistemụ kemịkalị na imeju. Hormones dịkwa na mmiri ara ehi ma kwado mgbaze nkịtị na obere eriri afọ.
Mgbe nkụ na-abanye n'ihe oriri nke pancreas, a na-enyefe ya ihe ọ na-aza site na iwepu ego dị mkpa iji nwee nsogbu. O nwere enzymes pancreatic n'ụdị arụ ọrụ - proenzymes.
A na-akpọ duct ahụ mmiri ihe ọreatụ pancụ na-abanye n'ime duodenum 12 ka ana-akpọ Virsungieva duct ma ọ dịkwa na ogologo nke gland niile. Ọ na-ejedebe n'azụ pancreas site na sphincter nke Oddi. N'ime ọtụtụ mmadụ, virsungiev duct na-ejikọ ya na otu ihe ọzọ na-eme ka ihe na-eme, ma gbasaa na duodenum.
Odogwu a na-emeghachi omume maka nri na-abata site na mwepụ nke bile, nke na-agwakọta na mmiri mmiri na ihe ọ pancụ pancụ azụ. Mgbe nke a gasịrị, mmebe nke enzymes maka ịhazi abụba, protein na carbohydrates na-amalite. N'okpuru mmetụta nke enzymatic ihe, carbohydrates dị mgbagwoju anya na-agbadata glucose, protein ruo amino acid, abụba abụba na glycerol.
Enzymes Pancreatic na-arụ ọrụ kachasị ego na mgbaze nri. Nri oriri nke enzymes na-abanye na obere eriri afọ, ebe a na-etinye nri na-edozi ahụ site na mgbidi eriri afọ n'ime ọbara, na-ebuga ha na akụkụ ahụ na anụ ahụ nke anụ ahụ.
Ebe ọ bụ na enzymes nke ọrụ pancreas mepụtara ebe usoro nri na-agbari ike, nsogbu niile dị na ahụ na-emetụta ọdịmma mmadụ. Enwere nsogbu na eriri afọ (stool iwe iwe), enwere dyspeptip ngosipụta - flatulence, bloating na ọgbụgbọ. N'ihi enweghi enzymes pancreatic, ọtụtụ ọgwụ ndị na-agbari agbari, ọ na-amalitekwa.
Chebe
Enwere ụdị enzymes atọ atọ - amylase, lipase na protease. Amylases na-agbari sitri na carbohydrates, ọrụ nke lipase bụ hydrolysis nke abụba, yana proteinase maka mmebi protein.
Otu nchekwa ahụ gụnyere exopeptidases, na-akụghasị agbụ peptide na mpụ na protein na peptides, na endopeptidases, bụ ndị na-ahụ maka hydrolysis nke agbụ protein-peptide. Exopeptidases gụnyere carboxypeptidase A na B, enzymes nchebe nke na-agbaji njikọ peptide ma bụrụ akụkụ nke nzuzo nzuzo.
Endopeptidases bụ pepsin, gastricin na chymosin, nke gastric mucosa na-ekpuchi, na progzymes trypsin, chymotrypsin na elastase. Enzymes caloos na-agbari ngwa ngwa protein, na-ejikọ hydrochloric acid ruo 95%.
Na-esote, enzymes a na-eme ka a na-ahụ maka ya bụ ọrụ, na-agbakwunye na-agbari protein na eriri afọ. Nke mbu, trypsin, chymotrypsin na elastase na-etisa nnukwu protein protein n'ime obere - peptides. Mgbe ahụ, n'okpuru ọrụ nke carbonxypeptidase, peptides na-agbanye mmiri n'ime amino acid nke mgbidi eriri afọ na-anabata.
Ihe ọ juiceụ 6ụ pancreatic nwere ụdị nchebe 6, nke dị iche na nhazi nke etiti ọrụ:
- serine;
- threonine;
- cysteine;
- aspartyl;
- metalloprotease;
- glutamine.
Ekwesịrị iburu n'uche na nchebe bụ akụkụ nke ọtụtụ ọgwụ nwere enzymes eji iji weghachi ọrụ pancreatic ma kpochapụ ihe mgbaàmà na-adịghị mma.
Amylase
Ammilolytic pancreatic enzymes na-akụda nri ndị na-eme ka ọ sie ike ghọọ shuga dị mfe a na-akpọ oligosaccharides. Ọ bụ ekele nke amylase na njiri mara ụtọ aftertaste pụtara mgbe eri nri dị ala - dịka ọmụmaatụ, osikapa ma ọ bụ nduku. Enzyme a dịkwa na mmiri, n'okpuru aka nke usoro nri nri na-amalite.
N’ọnụ ọnụ, a na-agbaji sitụrụ ruo dextrin, a na-etolitekwa dextrin na maltose n’ihi nhazi nke polysaccharides site na mmiri mkpụrụ osisi. Nzọụkwụ ikpeazụ bụ njedebe nke carbohydrates na duodenum 12 n'ime glucose na fructose n'okpuru ọrụ Y-amylase.
Enzymes amylolytic gụnyere lactase, nke na-akụri lactose (shuga mmiri ara ehi) dị na ngwaahịa mmiri ara ehi.
Enzyme erughi nke amylase nwere ike igosipụta mmepe nke ọtụtụ pathologies: pancreatitis, mumps (mumps), diabetes mellitus na etuto ahụ.
Lipase
Enzymes Lipolytic na-arụ ọrụ dị ka ihe na - eme ka mmiri na - egbu egbu ma na - agbasa abụba enwetara na ahụ. Lipase na-arụ ọrụ n’ime eriri afọ ma mebie nri ndị nwere abụba n’ime glycerin na abụba bara ụba. A na - ekeji enzyme a n'akụkụ hydrophilic na hydrophobic nke na - arụ ọrụ naanị na mmiri nke nwere abụba. Yabụ, ihe dị mkpa iji gwuo maka abụba bụ iberibe ha n'ime obere iberibe bile - yabụ, mpaghara metụtara lipase na-abawanye.
A na-ahụta ọkwa lipase na nnwale ọbara maka ọrịa dị iche iche nke eriri afọ na akụrụ, ọrịa metabolic (ọrịa shuga, gout, oke ibu), peritonitis, na mumps. N'ụfọdụ, mkpụrụedemede egbugbere ọnụ na-abawanye n'ihi ọgwụgwọ ogologo oge yana barbiturates, narcotic analgesics, Heparin na Indomethacin.
Ọ bụrụ na lipase ezughị ezu n'ahụ ahụ, mgbe ahụ ihe kpatara ya nwere ike bụrụ mbelata nke ọrụ pancreatic, cystic fibrosis (cystic fibrosis), mmepe nke neoplasms ọjọọ na akụkụ ọ bụla ma e wezụga pancreas. Mgbe ụfọdụ, nri dị ala na-adịkarị ala n'ihi nri anaghị edozi onwe ya na nri nke abụba buru ibu.
Nchoputa ya na ihe iriba ama nke oru ihe omimi
Iji chọpụta enzymes nke pancreas anaghị amịpụta na ọnụọgụ zuru ezu, a na-eme nyocha ụlọ nyocha. Dabere na nsonaazụ nke nyocha ọbara, mmamịrị na feces, ọmụmụ ọrụ, yana na-ebukwa n'uche mgbaàmà ndị dị adị, enwere ike ịkọ usoro enzyme.
Forkpụrụ maka ọdịnaya nke enzymes bụ ndị a:
- ọbara: amylase - 29-99, lipase - 22-66, trypsin - 19.7 - 30.3 mg / l;
- ọbara ọbara: elastase - 01 - 4 ng / ml;
- mmamịrị: amylase (diastase) - max 100 nkeji / l;
- coprogram: elastase - site na 200 mcg / g.
A na-emepụta enzymes Pancreatic n'ime mkpụrụ ndụ acinar nke pancreas, mgbe ahụ site na ntakịrị ntakịrị ha na-abanye ọdụ mmiri buru ibu nke na-etolite isi mmiri - Virsungs
Enweghi nke enzymes pancreatic na-eduga na nnukwu mmebi nke ọrụ digestive na anụ ahụ niile. N'ihe banyere imepụta enzymes nke ukwuu, a na-achọpụta ọnya na-egbu egbu nke pancreas - pancreatitis. Mbelata njikọ nke enzymes pụtara ngbanwe nke ọrịa ahụ n’ụdị na-adịghị ala ala.
Ihe ndị na-esote ya nwere ike ibute mgbanwe mkpali na mbibi na pancreas ma dochie anụ ahụ glandular na anụ ahụ na - emeju:
- ị andụbiga mmanya ókè na ị abuseụbiga mmanya ókè, mmanya na-egbu egbu;
- ọnụnọ nke neoplasms - cysts, etuto (ma ọ bụ ụkọ ma ọ bụ nke jọgburu onwe), fibrosis;
- pathology nke duodenum na traktị biliary;
- ịwa ahụ.
Site na ụkọ nke enzymes, ọtụtụ njirimara njirimara bilitere:
Etu ị ga-esi lelee pancreas- polyfecal (nnukwu ego dị iche iche feces)
- ihe eji esi nri, okpukpo ahihia di iche iche nke agba agba agba nwere odo nke akpukpo ahihia ma na adighi nma;
- ọnụnọ nke iberibe nri iberibe nri na ahịhịa;
- mmetụta nke afọ ju afọ na ọgbụgbọ, obi mgbawa;
- uto ojoo na onu;
- agụụ riri;
- mẹ iphe, dụ ẹji;
- ịba oke ibu, anaemia, adịghị ike, ehighi ura na isi ọwụwa;
- afọ mgbu mgbe ị risịrị nri;
- anabataghị nri na abụba na nri.
Ebe ọ bụ na a na - ebelata njikọta lipase n'ụzọ dị ala, nsogbu ọgbụgba bụ otu n'ime ndị mbụ - ọ na - aghọ viscous ma ọ bụ ọkara mmiri. Ọ dị mma ịmara na ihe mgbaàmà ndị ahụ bụ otu ihe na enzymes karịrị, yana enweghị ụkọ. Na agbanyeghị, n'ihe banyere imepụta enzymes gabigara ókè, okpomoku ahụ nwere ike ịba ụba, ọrịa mgbu ahụ wee pụta nkọ.
Mmebi nke ọrụ exocrine nke pancreas chọrọ ọgwụgwọ mmado, ebe ọ nwere ike ibute mmepe nke ọrịa ndị dị egwu dịka akwara na-egbu mgbu, ọnya afọ, ịba ọcha n'anya na ọrịa nrịanrịa.
Ọgwụ Enzyme nwere ọgwụ
Edebere enzymes maka nsogbu a dabere na nsonaazụ nyocha a dabere na mgbaàmà ndị dị adị. Usoro usoro onunu ogwu ya na usoro onwonye ya dabere n’afọ na ogo nke onye ọrịa, yana n’ụdị ọrịa ahụ. Na ọgwụ nnọchi enzyme, a na-eji ọgwụ ndị gụnyere lipase, amylase na trypsin. Nke a bụ, nke mbu, Pancreatin na usoro ya - Creon, Mezim Forte, Pangrol, Panzitrat, wdg.
Ọtụtụ mgbe, ndị dọkịta na-atụ aro ị Creụ Creon, ebe ọ ka amaka karịa ma nwee nnukwu uru. Creon adịghị na mbadamba, mana capsules nwere nchekwa abụọ. Capsule ọ bụla nwere ọtụtụ mini-microspheres, nke na-adaghị n'okpuru ike nke hydrochloric acid nke afọ ma ruo ebe ha na-aga - n'ime eriri afọ. Na mgbakwunye, ihe mejupụtara nke Creon gụnyere dimethicone, nke na-ebelata ike ikuku.
Otutu ogwu nwere ihe mejuputara, emeju ya na ihe mebiri emebi. Edere ha ha maka ọrịa na-emetụta ọnya na eriri afọ. Ngwakọta ọgwụ gụnyere Festal, Digestal, Kotazim Forte, Enzistal.
The unienzyme dabere na osisi enzyme papain na-akwalite mgbaze zuru oke nke protein, abụba na carbohydrates, nwere ihe na-adọrọ adọrọ, ihe na-egbu egbu ma na-ebelata ike nke ikuku.
Na nnukwu ọrịa a na - egbochi enzyme na - egbochi ọrụ pancreas - Somatostatin, Kontrikal, Ingitril, Glucagon, Gordoks, wdg.
N'ihe banyere njehie na nri nri ma ọ bụ jiri mgbaàmà dị nro nke ọrịa pancreatitis, enwere ike iji enzymes osisi - dịka ọmụmaatụ, Oraza, Pepfiz, Unienzyme, Wobenzym, Solizim, Abomin.
Uru nri
Iji nweta nsonaazụ kachasị site na ọgwụgwọ na ndị nnọchi enzyme, ịchọrọ nri kwesịrị ekwesị. Ọ dabere na ụkpụrụ nke nri Nke 5, na-eme ka mgbake dị ukwuu karị:
- okpukpu abuo - onu ogugu nri kwa ubochi erughi 5;
- ịdị arọ nke otu onye na-eje ozi ekwesịghị gafere 200 g.
- a na-asacha efere niile, na ite ma ọ bụ sie;
- nri nri - ihe dịka 35-40 Celsius;
- amachibidoro abụba, eghe, mmanya.
Steam anụ na azụ nke ụdị obere abụba, àkwá ọkụkọ, buckwheat, oatmeal, apụl, unere na chiiz ụlọ ka akwadoro maka iji ya.
Iji weghachi ọrụ nke akwara site na nhazi enzyme, nyocha dị mkpa. Dabere na nsonaazụ ndị ọrịa ọ bụla, a na-ahọrọ usoro ọgwụgwọ otu na usoro ị drugsụ ọgwụ.
