Traditionzọ ọdịnala iji belata shuga mgbe ị risịrị nri gụnyere insulins mmadụ na-eme mkpụmkpụ. Otu n'ime ọgwụ ndị ewu ewu, Actrapid, na-alụ ọgụ ọrịa shuga kemgbe ihe karịrị afọ iri atọ. N'ime ọtụtụ afọ, ọ gosipụtala ezigbo mma ya ma zọpụta ọtụtụ nde ndụ.
Ka ọ dị ugbu a, insulins ọhụụ dị ugbua adịlarị na -emepụta glycemia nkịtị ma nwekwa nsogbu site na ndị bu ha ụzọ. N'agbanyeghi nke a, Actrapid anaghị ada mba ọ nọ ma jiri ya rụọ ọrụ na-agwọ ụdị shuga nke 2 na ụdị nke abụọ.
Ntụziaka dị mkpirikpi maka ojiji
Actrapid bụ otu n'ime ihe mbụ ebupụtara site na usoro inyocha mkpụrụ ndụ ihe nketa. Emepụtara ya na 1982 bụ ọgwụ ọgwụ Novo Nordisk, otu n'ime ndị kachasị mmepe nke ọgwụ shuga n'ụwa. N'oge ahụ, ndị ọrịa mamịrị nwere afọ ojuju na insulin anụmanụ, nke nwere ntakịrị mmacha yana oke allergenicity.
Ọrịa shuga na oke nrụgide ga-abụ ihe mgbe ochie
- Normalization shuga -95%
- Mwepu nke akwara mbufụt - 70%
- Mwepu nke obi ike -90%
- Bibie ọbara mgbali elu - 92%
- Mmụba na ume n'ụbọchị, na-eme ka ụra na-ehi ụra n'abalị -97%
A na - enweta ọgwụ eji eme ihe site na iji ọgwụ nje emegharị, ngwaahịa a rụchara arụcha na - ekwughachi insulin emepụtara n'ime mmadụ. Teknụzụ mmepụta ahụ na-enye aka nweta ezigbo hypoglycemic mmetụta na ịdị ọcha dị elu nke ihe ngwọta, nke belatara ihe ize ndụ nke allergies na mkpali na ntanetị. Rada (edebanye aha ọgwụ nke Ministrylọ Ọrụ Ahụike debara aha) na-egosi na enwere ike ịhazi ọgwụ ahụ ma kee ya na Denmark, France na Brazil. A na-achịkwa njikwa nke ngwaahịa ahụ naanị na Europe, yabụ enweghị obi abụọ ọ bụla banyere ogo ọgwụ ahụ.
Ozi dị mkpirikpi banyere Actrapide site na ntuziaka maka ojiji nke ọrịa shuga ọ bụla kwesịrị ịma:
| Ihe omume | Ọ na-akpali ntụgharị nke shuga site n'ọbara na akwara, na-eme ka njikọ nke glycogen, protein na abụba na-aga n'ihu. |
| Ngwakọta |
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| Ihe ngosi |
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| Ihe ngbanwe | Mmeghachi omume onwe onye site na sistemụ ahụ na - adịghị akwụsị izu abụọ site na mmalite nke insulin insulin ma ọ bụ na - apụta na ụdị siri ike:
Arụ Ọrụ amachibidoro iji nfuli insulin, ebe ọ bụ na ọ na-adịkarị na mkpu mkpu ma nwee ike iweghasị usoro infusion. |
| Dose nhọrọ | Operapid dị mkpa iji kwụọ glucose na-abanye n'ọbara ọbara mgbe ị risịrị nri. A na-agbakọta ọ̀tụ̀tụ̀ ọgwụ a n ’ịgwọ ya site n’ókè nke carbohydrates dị na nri. You nwere ike iji usoro achịcha achịcha. A na-ekpebi olu insulin na 1XE site na ịgbakọ ọnụ, a na-edozi coefficients ọ bụla dịka nsonaazụ nke glycemia si dị. A na-ahụ usoro onunu ogwu ahụ dị mma ma ọ bụrụ na shuga ọbara laghachiri ọkwa mbụ ya mgbe ọ rụsịrị ọrụ insulin. |
| Achọghị ihe ọ bụla | Ọ bụrụ n ’usoro a gafere gabiga ya, hypoglycemia na - apụta, nke nwere ike ibute coma n’ime otu elekere. Udiri shuga na -emekarị ugboro ugboro na-emebi mmebi akwara, na-ewepụ ihe mgbaàmà hypoglycemia, na-eme ka o sie ike ịchọpụta. N'ọnọdụ nke imebi usoro injection nke insulpid insulin ma ọ bụ n'ihi njirimara nke akụkụ anụ ahụ dị n'okpuru ala, lipodystrophy ga-ekwe omume, ugboro ole ha na-eme erughị 1%. Dịka ntuziaka ahụ si dị, mgbe ị na-agbanwe insulin na ọdịda shuga ngwa ngwa, mmeghachi omume n'akụkụ nwa oge nke na-apụ n'anya nke onwe ha ga-ekwe omume: ọhụhụ anya, ọzịza, neuropathy. |
| Njikọ ya na ọgwụ ndị ọzọ | Insulin bụ nkwadebe siri ike, n'otu sirinji enwere ike ịgwakọta ya naanị na nnu si na insulins ndị na-ajụ, ka nke otu emeputa (Protafan). Ọ dị mkpa iji mee ka insulin insulin jupụta n'ọrịa ndị ọrịa shuga nke nwere nnukwu ọganụ na homonụ, dịka ọmụmaatụ, ụmụaka. Ejikọtara ya na ọgwụ ndị na-eme ihe maka ụdị shuga 2, na-abụkarị ndị agadi. Drugs drugsụ ọgwụ ụfọdụ n’otu oge nwere ike imetụta ọrụ insulin. Hormonal na diuretics nwere ike ịkụda nsonaazụ nke Actrapid, na ọgwụ ọgbara ọhụrụ maka nrụgide na ọbụna tetracycline nwere ọgwụ aspirin nwere ike iwusi ya ike. Ndị ọrịa na ọgwụ insulin kwesịrị iji nlezianya mụọ ngalaba "Mmekọrịta" na ntuziaka nke ọgwụ niile ha na-eme atụmatụ iji. Ọ bụrụ na ọgwụ a nwere ike imetụta ihe insulin na-eme, a ga-agbanwe usoro onodu ogwu nke Actrapid nwa oge. |
| Ime na GV | N'oge omumu na lactation Actrapid ka a na-anabata. Ọgwụ a anaghị agafe Plasenta, ya mere, enweghị ike imetụta mmepe nke nwa ebu n’afọ. Ọ na-abanye n'ime mmiri ara ara n'ọtụtụ micro, emesia kewaa ya na ngọngọ nwa. |
| Releasedị ntọhapụ insulin na-arụ ọrụ | Rada gụnyere ụdị ọgwụ atọ a na-anabata maka ire na Russia:
Na omume, naanị karama (Actrapid NM) na katridges (Actrapid NM Penfill) na-ere. Formsdị niile nwere otu nkwadebe na nchịkọta nke 100 nkeji insulin kwa mililiter nke ihe ngwọta. |
| Nchekwa | Mgbe emepechara, a na-echekwa insulin ahụ maka izu isii n’ebe gbara ọchịchịrị, oke ọkụ kwere ka ogo 30 Celsius. A ga-eme ka nkwakọ ngwaahịa spare. Anabataghị ị freeụ insulin nke na-eme ihe. Lee ebe a >> iwu izugbe maka nchekwa insulin. |
A na-etinye Actrapid kwa afọ na ndepụta ọgwụ ọjọọ dị oke mkpa yana ihe dị mkpa, yabụ ndị ọrịa mamịrị nwere ike inweta ya n’efu, na ndenye dọkịta gị.
Ozi ndi ozo
Actrapid NM na-ezo aka na mkpụmkpụ (ndepụta nke insulins dị mkpụmkpụ), mana ọ bụghị ọgwụ ultrashort. Ọ na-amalite ime ihe mgbe nkeji iri atọ gasịrị, yabụ ha na-ewebata ya tupu oge eruo. Ọrịa glucose sitere na nri nwere GI dị ala (dịka ọmụmaatụ, buckwheat na anụ) na-ejide “ijide” insulin a ma wepụ ya n'ọbara n'oge oge. Site na ngwa ngwa carbohydrates ngwa ngwa (dịka ọmụmaatụ, tii na achicha), Actrapid enweghị ike ịlụ ọgụ ngwa ngwa, yabụ mgbe ị eatingụ hyperglycemia ga-emerịrị, nke ga-eji nwayọ belata. Ọ bụghị nanị na ụdị shuga dị otú a na-eme ka ọdịmma onye ọrịa ka njọ, kamakwa ọ na-eme ka ọganihu nke ọrịa shuga na-akpata. Iji mee ka uto nke glycemia belata, nri ọ bụla nwere insulin Actrapid kwesịrị inwe eriri, protein, ma ọ bụ abụba.
Oge ọrụ
Actrapid na-arụ ọrụ ruo elekere asatọ. Oge awa ise mbụ - ihe bụ isi, emesia - ngosipụta ndị ọzọ. Ọ bụrụ na a na-ahụ insulin ugboro ugboro, nsonaazụ nke doses abụọ ga-ejikọ ibe ha. N'otu oge ahụ, ọ gaghị ekwe omume ịgụta usoro ị theụ ọgwụ a chọrọ, nke na-abawanye ihe ize ndụ nke hypoglycemia. Iji were ọgwụ ọfụma na-eme nke ọma, ọ dị mkpa ka ekesaa nri na inje inulin ọ bụla kwa awa 5.
Ọgwụ ahụ nwere oke arụmọrụ mgbe awa 1.5-3.5 gachara. N'oge a, ọtụtụ nri nwere oge mgbari, yabụ hypoglycemia na-apụta. Iji zere ya, ịchọrọ nri maka 1-2 XE. Na mkpokọta, na-arịa ọrịa shuga mellitus kwa ụbọchị, a na-enweta 3 isi na nri 3 ọzọ. A na - enye insulin Actrapid naanị tupu ndị bụ isi, mana a na-agbakọ usoro iji ya eme ihe na-eburu n'uche nri.
Iwu mmeghe
Enwere ike iji vials nwere Actrapid HM nwere insulin syringes akpọrọ U-100. Cartridges - ya na ogwe na sirinji: NovoPen 4 (usoro onunu ogwu 1), NovoPen Echo (0.5 unit).
Iji mee ka insulin rụọ ọrụ nke ọma na ọrịa mellitus, ọ dị mkpa ka ị mụọ usoro ntụtụ ahụ na ntuziaka maka iji ma soro ya. Ọtụtụ mgbe, a na-agbanye Actrapid n'ime mmanu na-eme n'afọ, a na-edebe sirinji n'akụkụ akụkụ ahụ. Mgbe itinyechara ya, anaghị ewepụ agịga ahụ ruo ọtụtụ sekọnd iji gbochie ngwọta ahụ ịpụta. Insulin kwesịrị ịdị n ’ọnọdụ ụlọ. Tupu nchịkwa, ọ dị mkpa ịlele ụbọchị ngafe na ọdịdị nke ọgwụ.
A machibidoro karama nwere ọka, sedimenti ma ọ bụ kristal n’ime ime.
Tụnyere ihe ndị ọzọ insulins
N'agbanyeghị eziokwu ahụ bụ na mora Actrapid dị na insulin mmadụ, mmetụta ha dị iche. Nke a bụ n'ihi nchịkwa ọgwụ subcutaneous. Ọ chọrọ oge iji hapụ anụ abụba wee rute n'ọbara. Na mgbakwunye, insulin na-adịkarịzi ike n’inwe usoro dị omimi n’ime akwara, nke na-egbochikwa mbelata shuga ngwa ngwa.
A na - anapụkwa ndị insulins ndị ọzọ ultrashort n'oge a - Humalog, NovoRapid na Apidra - adịghị ike ndị a. Ha na-amalite ịrụ ọrụ na mbụ, yabụ ha na-ejikwa wepu carbohydrates ngwa ngwa. Oge ha na-ebelata, ọ nweghịkwa ọnụ ọgụgụ kacha elu, ya mere nri nwere ike ịdị ọtụtụ ugboro, nri adịghị mkpa. Dabere na ọmụmụ, ọgwụ ultrashort na-enye njikwa glycemic ka mma karịa Actrapid.
Uzo eji insul na-eme insulin maka oria shuga nwere ike ikwenye ekwenye:
- n'ime ndị ọrịa na-agbaso nri obere carb, karịsịa na ụdị shuga 2;
- n'ime ụmụ nke na-eri nri kwa awa 3.
Ego ole bụ ọgwụ ahụ? Uru ndị a na-ejighị n’aka nke insulin a bụ obere ọnụahịa ya: otu 1 nke Actrapid na-akwụ 40 kopecks (400 rubles kwa karama 10 ml), homonụ ultrashort - ugboro atọ dị ọnụ karịa.
Analogs
Nkwadebe insulin na-eme mmadụ nwere ihe dị n'ime ala na ihe Njirimara yiri:
| Analogs | Emeputa | Ọnụahịa, tee. | |
| katọn | karama | ||
| Actrapid NM | Denmark, Novo Nordisk | 905 | 405 |
| Biosulin P | Russia, Onye na-ere ọgwụ | 1115 | 520 |
| Insuman Rapid GT | Belarus, Monoinsulin nke Czech Republic | - | 330 |
| Humulin Regular | USA, Eli Lily | 1150 | 600 |
Mgbanwe site na insulin gaa na nke ọzọ ga-eme naanị n'ihi ihe gbasara ahụike, ebe ọ bụ na akwụ ụgwọ nke ọrịa shuga ga-emerịrị njọ n'oge nhọrọ nke usoro.
Ọ ga-adị n’isiokwu: otu esi gbakọọ ọgwụ insulin maka ntụtụ
