Rosuvastatin SZ (North Star) so na otu nke statins nwere mmetụta na-ebelata.
A na-eji ọgwụ ahụ eme ihe n'ụzọ dị irè na ọrịa ndị metụtara metabolism na-emebi emebi, yana maka mgbochi nke ụfọdụ ọrịa pathologies. Enwere ike ịchọta ozi ndị ọzọ gbasara ọgwụ ahụ na ihe a.
Na ahịa ọgwụ, ị nwere ike ịchọta ọtụtụ ọgwụ nwere ihe rosuvastatin dị ike, n'okpuru ụdị dị iche iche. A na-emepụta Rosuvastatin SZ site na onye na-emepụta ụlọ North Star.
Otu mbadamba ụrọ nwere 5, 10, 20, ma ọ bụ 40 mg nke calsu rosuvastatin. Isi ya gụnyere shuga mmiri ara ehi, povidone, sodium stearyl fumarate, primellose, MCC, aerosil na calcium hydrophosphate dihydrate. Mbadamba ụrọ Rosuvastatin SZ bụ biconvex, nwere okirikiri ma kpuchie ya na mpempe pink.
Akụkụ nọ n'ọrụ bụ ihe na-egbochi HMG-CoA reductase. Ebumnuche ya bụ ịba ụba ọnụ ọgụgụ enzymes hepatic LDL, mee ka nkwalite LDL belata ma belata ọnụ ọgụgụ ha.
N'ihi iji ọgwụ ahụ eme ihe, onye ọrịa ahụ na-ejikwa belata cholesterol nke "ọjọọ" ma bulie itinye uche nke "ihe ọma". Enwere ike ịhụ ezigbo mmetụta ugbua ụbọchị 7 mgbe mmalite ọgwụgwọ, ma mgbe ụbọchị 14 gasịrị enwere ike ịnweta 90% nke mmetụta kachasị. Mgbe mkpụrụ ụbọchị iri abụọ na asatọ gachara, mkpụrụ ndụ na -emeghachi uru ọcha, ma mesịa chọọ ọgwụgwọ mmezi.
A na-ahụ ọdịnaya kachasị elu nke rosuvastatin 5 awa mgbe nchịkwa ọnụ.
Ihe fọrọ nke nta ka ọ bụrụ 90% nke ihe na-arụ ọrụ na-ejikọ ya na albumin. Nwepu ya n’arụ n’arụ n’arụ yana akụrụ.
Ihe ngosi na contraindications maka ojiji
Edere Rosuvastatin-SZ maka nkwarụ metabolism yana mgbochi nke ọrịa obi.
Dịka iwu, iji mbadamba nkume ndị a chọrọ ịgbaso nri hypocholesterol na egwuregwu.
Mpempe akwụkwọ ntụziaka a nwere ihe ngosi ndị a maka ojiji:
- mbu, famzyl nke ezinụlọ ma ọ bụ hypercholesterolemia agwakọta (dị ka mgbakwunye na usoro ọgwụgwọ abụghị ọgwụ);
- hypertriglyceridemia (IV) dị ka mgbakwunye maka nri pụrụ iche;
- atherosclerosis (igbochi ichebe akwa nke cholesterol ma mezie ogo nke cholesterol na LDL).
- igbochi ọnya afọ, nwughari akwara na nkụchi obi (ọ bụrụ na enwere ihe dịka ịka nká, ọkwa protein nke C-reactive, sịga, mkpụrụ ndụ ihe nketa na ọbara mgbali elu).
Dọkịta machibidoro ị theụ ọgwụ Rosuvastatin SZ 10mg, 20mg na 40mg ọ bụrụ na ọ chọpụta na onye ọrịa:
- Onwe onye n’onwe ya na mmiri.
- Okpu renal siri ike (ya na CC <30 ml / min).
- Malabsorption glucose-galactose, enweghị nke lactase ma ọ bụ enweghị nke lactose.
- Afọ n’afọ iri na asatọ;
- Ọrịa imeju na-aga n'ihu.
- Njuputa nke oria HIV na cyclosporin mgbochi.
- Ex gafere ọkwa CPK ugboro ise ma ọ bụ karịa karịa ala ala nkịtị.
- Ume nwere nsogbu myotoxic.
- Ime na oge ịra nwa.
- Enweghị mgbochi afọ nwanyị (na ụmụ nwanyị).
A na-agbakwunye contraindications maka iji Rosuvastatin SZ na usoro onunu ogwu nke 40 mg na mgbakwunye ndị a dị n'elu:
- agafeghị oke na nnukwu akụrụ ọdịda;
- hypothyroidism;
- nke agbụrụ Mongoloid;
- mmanya riri ahụ;
- ọnọdụ na-eme ka mmụba nke ọkwa rosuvastatin.
Ọzọkwa contraindication bụ ọnụnọ na akụkọ onwe onye / ezinụlọ nke akwara olu.
Ntuziaka maka iji ọgwụ ahụ
E kwesịrị iji mmiri ọ .ụ swallowụ rie mbadamba. A na-ewere ha n'agbanyeghị nri n'oge ọ bụla n'ụbọchị.
Tupu ịmalite na n'oge ọgwụgwọ ọgwụ, onye ọrịa ahụ na-ajụ ngwaahịa ndị dị ka ntinye (akụrụ, ụbụrụ), yolks, anụ ezi, mmanu abuba, nri ndi ozo abuba, ihe eji esi nri, achicha achicha na uto.
Dọkịta na-ekpebi usoro ị theụ ọgwụ ahụ dabere na ọkwa cholesterol, ebumnuche ọgwụgwọ yana njiri mara onye ọrịa ahụ.
Mkpụrụ mbụ nke rosuvastatin bụ 5-10 mg kwa ụbọchị. Ọ bụrụ na ọ gaghị ekwe omume iru nsonaazụ achọrọ, a na-amụba usoro ọgwụ ahụ ruo 20 mg n'okpuru nlekọta siri ike nke ọkachamara. Ọ dịkwa mkpa iji nlezianya na-elele 40 mg nke ọgwụ ahụ, mgbe a chọpụtara onye ọrịa na-arịa ọrịa hypercholesterolemia na oke ohere nke nsogbu obi.
-28bọchị 14-28 ka mmalite ọgwụgwọ ọgwụ dị, ọ dị mkpa iji nyochaa metabolism lipid.
Ọ dịghị mkpa ịhazigharị ọgwụ ole ọ toụrụ ọgwụ ahụ nye ndị ọrịa agadi na ndị nwere nsogbu nrụrụ akụrụ. Site na polyformism mkpụrụ ndụ, ebumnuche nke myopathy ma ọ bụ nke agbụrụ Mongoloid, dose nke ihe na-egbu egbu ekwesịghị ịfe 20 mg.
Usoro nchekwa okpomọkụ nke ịchekwa nkwakọ ngwaahịa ọgwụ adịghị ihe karịrị 25 Celsius. Ndụ shelf bụ afọ 3. Debe nkwakọ ngwaahịa ebe echekwara na mmiri na anwụ.
Mmetụta Ọkụ na Nnwekọrịta
A kọwara ntụpọ mmetụta niile ọ bụla enwere ike ị whenụ mgbe ị na-eji ọgwụ ahụ na ntuziaka maka ojiji.
Dịka iwu, mmetụta ndị ọzọ na-akpata mgbe ị na-a thisụ ọgwụ a dị ụkọ.
Ọbụna na ọdịdị nke mmeghachi omume na-adịghị mma, ha dị nwayọọ ma na-ahapụ onwe ha.
Ntuziaka maka ojiji, usoro ndị a ka egosipụtara:
- Usoro endocrine: mmepe nke ọrịa mellitus na-abụghị insulin na-adabere (ụdị 2).
- Sistemụ immune: Quincke edema na mmeghachi hyperensitivity ndị ọzọ.
- CNS: dizziness na migraine.
- Usoro ure: proteinuria.
- Afọ akpa umeji: ọnyụnyụ dyspeptik, ihe mgbu epigastric.
- Usoro akwara: myalgia, myositis, myopathy, rhabdomyolysis.
- Akpukpo ahu: itching, hives, na ihe nro.
- Usoro biliary: pancreatitis, nnukwu ọrụ nke transminases hepatic.
- Ndị na-egosi ụlọ nyocha: hyperglycemia, elu bilirubin, alkaline phosphatase, ọrụ GGT, dysfunction thyroid.
N'ihi nyocha azụmaahịa, a chọpụtara mmeghachi omume na-adịghị mma:
- thrombocytopenia;
- ọrịa jaundice na ịba ọcha n'anya;
- Stevens-Johnson syndrome;
- ncheta;
- afufu;
- polyneuropathy na-arịa ọrịa shuga;
- gynecomastia;
- hematuria;
- mkpụkpu ume na ụkwara;
- arthralgia.
N'ọnọdụ ụfọdụ, iji Rosuvastatin SZ na ọgwụ ndị ọzọ nwere ike ibute nsonaazụ na-enweghị atụ. N'okpuru bụ atụmatụ nke usoro nlekọta ọgwụ a n'otu oge na-ajụ ndị ọzọ:
- Na - ebugharị ndị na - egbochi protein - mmụba nke ohere myopathy na mmụba na ego nke rosuvastatin.
- Ihe mgbochi nje HIV - ekpughere ekpughe nke ihe arụ ọrụ.
- Cyclosporine - mmụba n'ọkwa nke rosuvastatin karịa ugboro asaa.
- Gemfibrozil, fenofibrate na fibrates ndị ọzọ, nicotinic acid - ihe dị elu nke ihe na-arụ ọrụ na ihe ize ndụ nke myopathy.
- Erythromycin na antacids nwere aluminom na magnesium hydroxide - mbelata ihe ndị dị na rosuvastatin.
- Ezetimibe - mmụba na ntinye nke mpaghara na-arụ ọrụ.
Iji gbochie mmepe nke mmeghachi omume na-adịghị mma n'ihi otu oge nke ọgwụ na-ekwekọghị ekwekọ, ọ dị mkpa ịgwa dọkịta banyere ọrịa niile na-agakọ.
Ọnụahịa, nyocha na analogues
Ebe ọ bụ ọgwụ Rosuvastatin na-emepụta ihe na-emepụta ọgwụ ụlọ "North Star", ọnụahịa ya adịghị elu. Nwere ike ịzụta ọgwụ n'ụlọ ahịa ọgwụ ọ bụla na obodo.
Ọnụahịa nke otu ngwugwu nwere mbadamba 30 nke 5 mg nke ọ bụla bụ 190 rubles; 10 mg nke ọ bụla - 320 rubles; 20 mg nke ọ bụla - 400 rubles; 40 mg nke ọ bụla - 740 rubles.
N'etiti ndị ọrịa na ndị dọkịta, ị nwere ike ịchọta ọtụtụ nyocha dị mma banyere ọgwụ. Nnukwu gbakwunyere bụ ọnụ ọnụ na-akwụ ụgwọ ma nwee mmetụta ọgwụgwọ dị ike. Ka o sina dị, mgbe ụfọdụ enwere nyocha na-adịghị mma nke metụtara ọnụnọ nke nsonaazụ.
Eugene: "Achọpụtara m ọgwụ metabolism ogologo oge gara aga. Anwale m ọtụtụ ọgwụ maka oge niile. Apụrụ m Liprimar na mbụ, ma kwụsị ya, n'ihi na ọnụ ahịa ya dị oke ọnụ. Krestor nyere m iwu, mana ọ mechara bụrụ ọgwụ adịghị ọnụ ala. Achọtara m onwe m analogues, nke bụ Rosuvastatin SZ. Ana m aillsụ ọgwụ ndị a, ọ dị m oke mma, cholesterol m alọghachila nkịtị. "
Tatyana: "N'oge ọkọchị, cholesterol dị elu ruru 10, mgbe ụkpụrụ dị ka 5.8. Agara m gaa therapist ma nye m ọgwụ Rosuvastatin .. Dọkịta ahụ kwuru na ọgwụ a nwere obere mmerụ ahụ na-emetụta imeju. mana enwere otu “mana” - oge ụfọdụ isi ọwụwa na-enye gị nsogbu. ”
A na-ahụ ihe mejupụtara rosuvastatin dị n'ọtụtụ ọgwụ ndị emepụtara site na ndị nrụpụta dị iche iche. Mmeghari gunyere:
- Akorta;
- Crestor
- Mertenyl;
- Rosart
- Ro-Statin;
- Rosistark;
- Rosuvastatin Canon;
- Roxer;
- Rustor.
Site na ịba ọcha n'anya nke rosuvastatin, dọkịta na-ahọrọ analogue dị mma, i.e. onye na - arụ ọrụ nke nwere ihe ọzọ na - arụ ọrụ na - arụ ọrụ, mana ọ na --emepụta otu mmetụta Lipid dị ala. N'ime ụlọ ahịa ọgwụ ị nwere ike ịzụta ụdị ọgwụ a:
- Atorvastatin.
- Atoris.
- Vasilip.
- Vero-simvastatin.
- Zokor.
- Simgal.
Isi ihe na ọgwụgwọ nke cholesterol dị elu bụ ịgbaso ndụmọdụ niile nke ndị ọkachamara na-abịa, soro usoro nri ma na-ebi ndụ dị mma. Yabụ, ọ ga-ekwe omume ịchịkwa ọrịa ahụ ma gbochie nsogbu dị iche iche.
A kọwara Rosuvastatin SZ ọgwụ ahụ n'ụzọ zuru ezu na vidiyo dị n'isiokwu a.
