SHORT INSULIN

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Insulin na-eme ihe nwa obere bụ ihe eji eme ka shuga na-ebelata ihe ndị na-eme ka carbohydrate dị n’ahụ.

Ihe mejupụtara ọgwụ a gụnyere ezigbo ọgwụ homonụ, nke enweghị ihe mgbakwunye ọ bụla nke na-eme ka ahụ ya dị ogologo. Otu ìgwè nke nwere ihe nwayo na-eme ngwa ngwa karịa ndị ọzọ, mana ngụkọta oge ha na-eme dị mkpụmkpụ.

A na-enweta ọgwụ intramuscular na enyo enyo mechiri emechi, jiri ya na ndị na-egbochi ya na nhazi nke aluminom.

Mmetụta insulin na-adị n'ahụ ahụ na-esonye:

igbochi ma ọ bụ mkpali nke enzymes ụfọdụ;
activation nke glycogen synthesis na hexokinase;
belata lipase na - eme mmanu mmanu.

Ogo nke nzuzo na biosynthesis dabere na oke glucose na n'ọbara. Site na mmụba na ọkwa ya, usoro nke imepụta insulin na pancreas na-abawanye ma, N'aka nke ọzọ, na-ebelata mkpụkọ, mmịpụta na-akwụsịlata.

Nhazi Insulin Short

Dabere na oge insulin na-eme ihe dị mkpirikpi bụ:

Short (soluble, ndị na - achịkwa) insulins - mee ihe mgbe nchịkwa gachara ọkara ọkara elekere, ya mere, a na-atụ aro ka ha jiri ya tupu nkeji iri anọ na iri ise tupu nri. Oke ruru nke ihe dị n'ọrụ ke n'ọbara ọbara rute mgbe awa 2 gachara, mgbe awa 6 gachara naanị ọgwụ ahụ ka na-aba n'ahụ. Short insulins gụnyere mmadụ nwere mkpụrụ ndụ ihe ọmụmụ, mkpụrụ ndụ ihe ọkụkụ yana anụ ezi soluble.
Ultrashort (mmadụ, analog) insulins - bido metụta ahụ mgbe nchịkwa gachara 15 nkeji. A na-arụkwa ọrụ ike mgbe awa ole na ole gasịrị. Nwepu zuru oke n’ahụ na-eme mgbe awa anọ gachara. N'ihi eziokwu ahụ bụ na ultrashort insulin nwere mmetụta physioloji karịa, enwere ike iji nkwadebe ndị dị na ya iji nkeji 5-10 tupu nri ma ọ bụ ozugbo nri. Ofdị ọgwụ a gụnyere insulin insulin na ụdị anaulin nke insulin.

Okwesiri iburu n'uche na insulin insulin yiri ihe mmeghachi omume nke ahụ mmadụ maka mmụba nke shuga ọbara mgbe ị risịrị. Ọ bụ ya mere o kwesịrị iji were obere oge tupu ma ọ bụ ozugbo nri.

Short insulin maka ọrịa shuga

Insulin insulin na - enyere aka igbochi mmepe nke nsogbu, mee ka ndụ onye ọria mamịrị dị ogologo ma melite ogo ya. Ọzọkwa, inje nke ọgwụ a na-ebelata ibu na pancreas, nke na-enyere aka weghachite akụkụ nke mkpụrụ ndụ beta.

Enwere ike imepụta ụdị ọrịa a na ụdị ọrịa shuga 2 na mmejuputa mmemme ọgwụgwọ na ịgbaso usoro dọkịta na-atụ aro. Iweghachite sel nke beta nwekwara ike ịrịa ọrịa shuga 1 naanị ma ọ bụrụ na emere nchọpụta ya n’oge ma were usoro ọgwụgwọ n’enweghi oge.
Dịka ọ dị, a na-enye ọgwụ ahụ intramuscularly ma ọ bụ subcutaneously nwere sirinji emebere nke insulin. Naanị ọnụnọ nke ọrịa mamịrị, a na-anabata nchịkwa intravenous ọgwụ. A na-ahọrọ usoro ọgwụgwọ ahụ n'otu n'otu, na-eburu n'uche ọrịa ahụ, ọkwa shuga dị n'ahụ ahụ na ọnọdụ onye ọrịa n'ozuzu ya.

E kenyere in insulin insulin n'ime 2-3 usoro kwa ụbọchị ọkara otu awa tupu nri. Ọgwụ mbụ nke ọgwụ a sitere na nkeji 10 ruo 40 kwa ụbọchị.

Site na coma mamịrị, achọrọ ọgwụ ka ukwuu: maka nchịkwa subcutaneous - site na 100 PIECES na elu, yana maka nchịkwa intravenous - ruo 50 PIECES kwa ụbọchị. Maka ọgwụgwọ nke taxuremy ọrịa shuga, a na-agbakọ ego nke insulin kwekọrọ na ogo nke ọrịa akpata. N’aka ndi ozo, achoghi oke onodu homonụ, ana akwado ya iweputa obere ogwu, mana karia.

Mmeghachi omume ọjọọ na contraraindications

Achọpụtaghị insulin maka iji ya:

ọria aru
ịba ọcha n'anya
jed

Ọrịa obi jọrọ njọ
ọrịa akụrụ
ọnya afọ nke eriri afọ na duodenum.

Mmeghachi omume ndị kachasị njọ mgbe nchịkwa nke wakpo homonụ na-apụta mgbe a naghị agbaso usoro usoro ọgwụgwọ. Nke a na-esokwa mmụba dị elu nke insulin n'ọbara.

Ọrịa ndị a na-ahụkarị bụ:

adịghị ike n'ozuzu;
ịsụsọ ọnụ;
palpitations
ụba salivation;
anya ntughari.

N'okwu ndị dị oke njọ nke mmụba dị egwu na homonụ n'ọbara (ma ọ bụrụ na enweghị nhazi oge nke carbohydrates), ịmị mkpụrụ nwere ike ime, tinyere mwepụ na ịma mma hypoglycemic.

Nkwadebe insulin dị mkpirikpi

Ọgwụ niile nwere obere insulins mmadụ ma ọ bụ analogues ha nwere njiri mara otu. Ya mere, ọ bụrụ na ọ dị mkpa, enwere ike dochie ha, na-ahụ otu usoro onunu ogwu, na oge ịgakwuru dọkịta ka achọrọ. Yabụ, obere nhọrọ aha insulin na-arụ ọrụ ma na-eme ngwa ngwa

Kacha ewu ewu na ọgwụ obere eme na-:

Actrapid (nkezi ọnụ ego nke 380 rubles)

emeputara site na iji Saccharomyces cerevisiae site na iji teknụzụ DNA arụmọrụ. Ogologo oge nke ihe ndi n’aru oru n’ahu n’ahu na-ekpebi site n’inwe ya. Ọ dabere na usoro onodu ogwu, mpaghara, ụdị ọrịa shuga mellitus na ụzọ nchịkwa. Mmetụta ọgwụ ahụ na-amalite mgbe nkeji iri atọ gasịrị. A na - enweta insulin kachasị n'ogologo oge dịka oge awa 1.5-3.5 na oge ihe ọ ga - eme dị iche ka awa asaa ruo awa asatọ.

Humulin (ụgwọ 530 rubles)

- ọgwụ nke nwere mmetụta hypoglycemic. Emebere ya site na insulin nke mmadu na –eme ihe, o metutara ndi na aru oru gi. Ọgwụ na-amalite ime ihe mgbe ochichi n'ime otu awa. A na-enweta ntinye uche kachasị mgbe awa 1-3 gachara, oge ngụkọ oge nke anụ ahụ bụ awa 5-8.

Iletin (nkezi ọnụ ahịa site na 400 rubles)

- ihe mejupụtara ọgwụ a gụnyere insulin-zinc anụ ezi monocomponent. Ọgwụ nwere obere oge na oge ekpughe, n’ihi mmịpụta nke ihe dị arụ ọrụ. Mmalite nke ekpughere ọgwụ na-apụta mgbe awa 2.5 gachara, nsonaazụ kachasị bụ site na awa 7 ruo 15. Anọpụrụ insulin zinc n'ahụ n'ahụ otu ụbọchị mgbe nchịkwa gasịrị.

Nkwadebe siri ike:

Novorapid (ọnụahịa 1700 rub.)

emeputara site na iji Saccharomyces cerevisiae nwere amino acid na aspartic acid. Ogologo oge ekpughere ọgwụ ahụ dị mkpụmkpụ karịa nke insulin na-arịa mmadụ. Mgbe nchịkwa gasịrị, ọrụ ya na-amalite n'ime nkeji 10-20. Oke ruru n’ọbara n’arịa mgbe awa 1-3 gachara. Omume ahụ na-adịgide mgbe ọ gbasịrị ruo awa 3 ruo ise.

Humalog (nkezi na-eri otu kọọtụ 550 rubles)

- Ihe atụ nke insulin nke mmadụ, gosipụtara site na mmalite ngwa ngwa na njedebe nke ịdị irè ma e jiri ya tụnyere ọgwụ ndị na-eme obere oge. Ọsọ nke nsonaazụ ya bụ n'ihi na monomeric Ọkpụkpọ nke molekul nke humalogue. Mgbe ogwu ogbugba gachara, ihe onye na - eme ka homonụ bidoro metụta ahụ mmadụ mgbe nkeji iri na ise gachara. A na-achọpụta oge nlele kacha elu mgbe nkeji 30 ma ọ bụ awa 2.5 gachara. Ọ ga - apụ apụ mgbe awa 3-4 gachara.

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