Neurobion bụ ọgwụ multivitamin ọhụụ. Mmetụta ọgwụgwọ nke ọgwụ ahụ bụ n'ihi thiamine, pyridoxine na cyanocobalamin. Ndị dọkịta na-edekarị ọgwụ iji gwọọ ọrịa nke sistem.
ATX
A11DB (Vitamin B1, B6 na B12).
Neurobion bụ ọgwụ multivitamin ọhụụ.
Weputara udi ya na ihe mebere ya
Na ahịa ọgwụ nke mba anyị, enwere ike ịzụta ọgwụ ahụ na mbadamba nkume na ampoules nke 3 ml.
Ere ọgwụ
Mbadamba nkume ndị ahụ bụ biconvex, kpuchie ya na shei ọcha dị ọcha. A na-egosi ngwakọta kemịkal nke ọgwụ ahụ na tebụl.
Ngwakọta | Otu mbadamba nwere mg |
Cyanocobalamin | 0,24 |
Pyridoxine hydrochloride | 0,20 |
Obi ọgbụgba | 0,10 |
Sucrose | 133,22 |
Ọka ọka | 20 |
Stereta magnesium | 2,14 |
Metocel | 4 |
Lactose Monohydrate | 40 |
Glutin | 23,76 |
Silica | 8,64 |
Mountain glycol wax | 300 |
Acacia arab | 1,96 |
Povidone | 4,32 |
Kaadị carbon | 8,64 |
Kaolin | 21,5 |
Glycerol 85% | 4,32 |
Titanium dioxide | 28 |
Talcum ntụ ntụ | 49,86 |
Mbadamba nkume ndị ahụ bụ biconvex, kpuchie ya na shei ọcha dị ọcha.
Ngwọta
Ọgwụ maka parenteral bụ mmiri doro anya uhie.
Ngwakọta | Otu ampoule nwere mg |
Cyanocobalamin | 1 |
Pyridoxine hydrochloride | 100 |
Thiamine hydrochloride | 100 |
Sodium hydroxide | 73 |
Potassium cyanide | 0,1 |
Mmiri mgbochi mmiri | ruru 3 cm3 |
Omume ọgwụ
Vitamin nke otu B, tinyere ihe omuma nke ogwu ahu, usoro ichogharia ihe omumu, dozie metabolism nke lipids, protein na carbohydrates. A dịghị etinye mmiri ọgwụ ndị a, n'adịghị ka analogues fat-soluble, n’anụ ahụ mmadụ, yabụ, ha ga-anọrịrị n ’ike zuru ezu banye n’ime ahụ nri ma ọ bụ dịka akụkụ nke vitamin-mineral supplements. Ọ bụrụ na obere oge iji nwude ha, na-ebelata ọrụ nke sistemụ enzyme, nke na-egbochi mmeghachi omume metabolic ma belata ọgụ.
Vitamin nke otu B, tinyere ihe omuma nke ogwu ahu, usoro catdoz catdox.
Mlọ ọgwụ
Site na ụkọ nke osisi nke ahụ na ahụ, a na-akpaghasị usoro ntụgharị nke pyruvate na acetate acid (acetyl-CoA) na-arụ ọrụ. N'ihi nke a, keto acid (α-ketoglutarate, puruvate) na-agbakọta na ọbara na anụ ahụ nke anụ ahụ, nke na-eduga 'acidification' nke anụ ahụ. Acidosis na-etolite ka oge na-aga.
Metabolites metabolites nke vitamin B1, thiamine pyrophosphate, na-eje ozi dị ka cofactor na-abụghị protein protein nke decarboxylases nke pyruvic na α-ketoglutaric acid (i.e., ọ na-ekere òkè na catalysis nke carbohydrate oxidation). A na - etinye Acetyl-CoA na okirikiri nke Krebs ma bụrụ nke e mere ka ọ bụrụ mmiri na carbon dioxide, ebe ọ bụ isi iyi nke ike. N'otu oge ahụ, thiamine hydrochloride na-etinye aka na nguzobe nke ọdụdụ abụba na cholesterol, na-eme ka usoro nke ịtụgharị carbohydrates abụba.
Mgbe ejiri ọnụ na-ekwu ya, iwepu ọkara ndụ maka vitamin B1 bụ ihe dịka awa anọ.
Mgbe ejiri ọnụ na-ekwu ya, iwepu ọkara ndụ maka vitamin B1 bụ ihe dịka awa anọ. N'ime imeju, phosphorylated nke mkpụrụ osisi a na-eji ọgwụ mkpụrụ osisi na-agbanwe agbanwe wee mee ka ọ bụrụ pyramhosphate. Ahụ dimkpa nwere ihe dịka 30 mg nke vitamin B1. Nyere oke ahụ ike siri dị, ewepụrụ ya n’ahụ n’ime ụbọchị 5-7.
Pyridoxine bụ ihe mebere coenzymes (pyridoxalphosphate, pyridoxamine phosphate). Site na ụkọ vitamin B6, mgbanwe nke amino acid, peptides na protein na-emebi. N'ime ọbara, ọnụ ọgụgụ sel ọbara ọbara na-ebelata, hemostasis na-akụghasị, oke nke protein protein na-agbanwe. N'okwu ndị dị oke omimi, ụkọ vitamin na-agwakọta mmiri na-eduga n'inwe mgbanwe nke anụ ahụ. Ahụ nwere ihe dịka 150 mg nke pyridoxine.
Site na ụkọ vitamin B6, mgbanwe nke amino acid, peptides na protein na-emebi.
Pyridoxalphosphate na-etinye aka na ịmepụta neurotransmitters na homonụ (acetylcholine, serotonin, taurine, histamine, tryptamine, adrenaline, norepinephrine). Pyridoxine na - emekwa ka biosynthesis nke sphingolipids, ihe mejupụtara akụkụ nke myelin sheaths nke eriri akwara.
Cyanocobalamin bụ vitamin nwere vitamin nke na-eme ka imepe sel sel ọbara dị, na-eme ka enzymes imeju na-egbochi ntụgharị carotenoids na retinol.
A chọrọ vitamin B12 maka njikọ nke deoxyribonucleic acid, homocysteine, adrenaline, methionine, norepinephrine, choline na creatine. Ngwakọta nke cyanocobalamin gụnyere cobalt, otu nucleotide na radieshọn radyanị. A na-edebe Vitamin B12 n’ime imeju.
A chọrọ Vitamin B12 maka njikọ nke deoxyribonucleic acid.
Ihe ngosi maka ojiji
Edere ọgwụ ahụ maka ọgwụgwọ nke ọrịa ndị a:
- radiculopathy;
- thoracalgia;
- ọrịa spinal (spondylarthrosis, osteochondrosis, spondylosis);
- ọrịa neuropathic;
- herpes zoster;
- trigeminal neuralgia;
- ọrịa lumbar;
- Bell na-egbu egbu;
- plexopathy.
Ihe ngbanwe
Ọgwụ nwere ọtụtụ contraindications na nhọpụta:
- thromboembolism;
- afọ ụmụaka;
- erythremia;
- hypernaiti;
- ọnya afọ;
- nke ahu anataghi
Etu ị ga-esi
Iji gbochie nlọghachi nke ọrịa ahụ, a na-enye ọgwụ a ka ọ bụrụ na mbadamba mbadamba, 1 capsule ugboro atọ n'ụbọchị. Mgbe ị na-a tabletsụ mbadamba, ị ga-a toụ ya ọtụtụ mmiri. Ọ bụ dibia bekee kpebisiri ike oge ọ ga-eji agwọ ọrịa.
Emeghachiri ọgwụ dị na ampoules maka nchịkwa intramuscular. Tupu iwepu isi ihe na-egosi oria a, a na-atụ aro ịbanye ọgwụ ahụ 1 oge kwa ụbọchị. Mgbe ahụ dị mma, a na-eme inje ugboro abụọ n'izu maka izu 2-3.
Na-arịa ọrịa shuga
Ngwá ọrụ dị n'elu dị mma maka ịgwọ mgbu neuropathic na ndị ọrịa na-arịa polyneuropathy mamịrị. Achọpụtara ya na ọgwụ ahụ na-ebelata ogo paresthesia, na-eme ka mmetụ anụ ahụ dị mma, belata ihe mgbu.
Iji gbochie nlọghachi nke ọrịa ahụ, a na-enye ọgwụ a ka ọ bụrụ na mbadamba mbadamba, 1 capsule ugboro atọ n'ụbọchị.
Nsonaazụ
Ọtụtụ ndị ọrịa na-anabata ọgwụ ahụ nke ọma. Ka osi di, n ’oge ụfọdụ, ngosipụta nke mmetụta ndị kewara n’otu n’otu ga-ekwe omume.
Ọkpụkpụ afọ
- ilo nri;
- vomiting
- hemorrhages na eriri afọ;
- mgbu afọ;
- ọgbụgbọ
- mẹ ivu;
- afọ ọsịsa
Site na usoro ahụ ji alụso ọrịa ọgụ
- Ire Quincke;
- ọrịa akpịrị;
- amu amu
- mmeghachi omume anaphylactoid.
Ahụhụ
- ihe odide
- itching
- hyperemia;
- ịatingụbiga mmanya ókè;
- mgbu
- ihe otutu
- urticaria;
- negiroscros na ebe ogwu ntụtụ.
Ọkpụkpụ akụrụngwa
- obi palp;
- obi mgbu.
Usoro ụjọ
- mgbakasị;
- migraine
- neuropathy sensọ;
- paresthesia;
- Obi erughị ala
- anya ntughari.
Ntụziaka pụrụ iche
Ebumnuche ọgwụ a abụghị maka ọgwụgwọ ọbara. Ọzọkwa, enweghi ike iji ọgwụ ahụ mee ihe na ndị ọrịa nwere nnukwu ọrịa obi. N'iji nlezianya dị elu, a ga-enye ndị mmadụ ọgwụ ọjọọ dị ka ọgwụ ọgwụ a.
Ebumnuche ọgwụ a abụghị maka ọgwụgwọ ọbara.
Mmetụta ikike ịchịkwa usoro
Ọgwụ a anaghị emetụta ikike mmadụ ịkwọ ụgbọ na usoro ndị siri ike.
Jiri n'oge ime na lactation
N'oge ị na-amụ nwa, enwere ike iji ngwaahịa ahụ ma ọ bụrụ na enwere ihe ịrịba ama doro anya nke ụkọ vitamin B1, B6 na B12 na ahụ nke nwanyị dị ime. Edebeghị nsonaazụ ọgwụ ahụ n'oge afọ ime, tupu ime na mgbe a mụpụtara nwa ahụ.
Dọkịta ga-ekpebi ịha kwesiri ekwesi ịcribụ ọgwụ ahụ n’oge afọ ime, chọpụta njikọ dị n’etiti uru na ihe ọghọm dị na ya.
E wepụrụ vitamin ndị mejupụtara ọgwụ ahụ na nzuzo nke mammary glands, n'agbanyeghị, ihe ize ndụ nke hypervitaminosis n'ime ụmụ amụrụbeghị. Ceptionnabata pyridoxine na oke ọnụọgụ (> 600 mg kwa ụbọchị) nwere ike ịkpalite hypo- ma ọ bụ agalactia.
N'oge ị na-amụ nwa, enwere ike iji ngwaahịa ahụ ma ọ bụrụ na enwere ihe ịrịba ama doro anya nke ụkọ vitamin B1, B6 na B12 na ahụ nke nwanyị dị ime.
Nhọpụta nke neurobion ụmụaka
Notmụaka na-erubeghị afọ 15 ka a na-atụ aro ịkọpụta ọgwụ.
Jiri na agadi
Ihe omuma banyere iji ogwu eme ihe n’ebe ndi agadi na ndi okenye no.
Dodoụbiga ya ókè
Na akwụkwọ pụrụ iche, akọwapụtara okwu banyere ịdoụ ọgwụ ókè na-adịghị ala ala. Ndị ọrịa na-eme mkpesa maka ahụike na-adịghị mma, akwara mgbu, nkwonkwo, ọgbụgbọ na ike ọgwụgwụ. Ọ bụrụ n’ịchọpụta akara ndị dị n’elu, ekwesịrị ịkagbu ọgwụ ahụ ma gakwuru dọkịta. Ọ ga - achọpụta ihe kpatara nsogbu ndị ahụ, kọwaa usoro ọgwụgwọ symptomatic.
Vitamin B1
Mgbe iwebata nke thiamine na dose karịrị akarị tụrụ aro karịa 100, hypercoagulation, nrụrụ purine na-akpata mmetụta, curariform ganglioblocklock mmetụta nke na-akpata mmetụ mmetụta nke mkpali n'akụkụ akwara akwara.
N’ewe ahụ ike, adịghị ike nke izugbe bụ ihe ịrịba ama nke ịdoụ ọgwụ ókè.
Vitamin B6
Mgbe nnabata ha dị ogologo (ihe karịrị ọnwa isii) nke pyridoxine na dose karịa 50 mg / ụbọchị, ngosipụta nke mmetụta neurotoxic (hypochromasia, seborrheic eczema, warakwụ, neuropathy na ataxia) ga-ekwe omume.
Vitamin B12
N'ihe banyere ịdoụbiga mmanya ókè, mmeghachi ahụ nfụkasị ahụ na-amalite, migraine, nsogbu ehighị ụra, akwara, ọbara mgbali elu, itching, nkwụsị nke oke ala, afọ ọsịsa, anaemia na ujo anafilactic.
Mmekọrịta na ọgwụ ndị ọzọ
Ntuziaka maka iji gosipụta na ọgwụ ụfọdụ ekwekọghị na ọgwụ a dị n'elu. Mgbe ụfọdụ, nlekọta ihe na - eduga na-akụda mmụọ nke ọgwụgwọ ọrịa ma ọ bụ na-abawanye na ngosipụta nke nsonaazụ ndị ọzọ:
- A na-emebi Thiamine site na mmekorita ya na ọgwụ nwere sulfites (potassium metabisulfite, potassium bisulfite, sodium hydrosulfite, sodium sulfite, wdg).
- Njikọ cycloserine na D-penicillamine jikọtara ọnụ na-eme ka ahụ mmadụ nwekwuo pyridoxine.
- Ekwesighi agwakọta ọgwụ a na ogwu ndi ozo n’otu syringe.
- Nlekọta nke ihe ana - eme ka ọ belata nha nke vitamin B1 n’ọbara ma na - eme ka ahụmmụta ya na - etochi ngwa ngwa.
Ekwesighi agwakọta ọgwụ a na ogwu ndi ozo n’otu syringe.
Onye ọrịa ga-agwa dọkịta banyere ọgwụ ndị ọ na - a currentlyụ ugbu a. Dọkịta n'okwu a ga-ahazigharị usoro ọgwụgwọ, si otú a belata ohere ị nwere ike inwe nsogbu ọ ga-enwe.
Analogs
Ọ bụrụ na ọ dị mkpa, enwere ike dochie ọgwụ ahụ:
- Neurolek;
- Kombilipen;
- Milgamma
- Vitaxone;
- Neuromax;
- Revalid;
- Neuromultivitis;
- Esmin;
- Neurobeks-Teva;
- Selmevite;
- Dynamizan;
- Unigamma
- Kombilipen;
- Centrum;
- Pantovigar;
- Farmaton
- Ginton;
- Nerviplex;
- Aktimunn;
- Berocca gbakwunyere;
- Enca;
- Detoxyl
- Pregnakea;
- Neovitam;
- ihe mgbagwoju nke vitamin B1, B12, B6;
- Megadine;
- Neurobeks-Forte.
Emeputa
Onye ọrụ ọgwụ a bụ Merck KGaA (Germany).
Ahịa ọgwụ na-ahapụ okwu
N’ebe a na-ere ọgwụ, a na-enye ọgwụ ndenye ọgwụ a, mana ọ bụghị ọgwụ a kapịtara ọnụ.
Ọnụ ego maka Neurobion
Ọnụ ego ọgwụ ọjọọ na Russia dịgasị na ọnụahịa ọnụahịa sitere na 220 ruo 340 rubles. Na Ukraine - 55-70 UAH. maka mbukota.
Ọnọdụ nchekwa nke ọgwụ Neurobion
Chekwaa ọgwụ a na ebe gbara ọchịchịrị ma dị jụụ.
Bọchị mmebi
Afọ 3
Nyocha nke ndị dọkịta na ndị ọrịa banyere Neurobion
Svetlana dị afọ 39, Kiev: "Enwere m nsogbu azụ azụ kemgbe m dị afọ 18. Achọpụtara ọrịa osteochondrosis Dọkịta tinyere ọgwụ vitamin ka injeram, ọgwụ amraule kwa ụbọchị 1 Mgbe ọ gwọchara ya izu abụọ, ahụike m kawanyere mma na mgbu mgbu mpaghara. Maka ebumnuche prophylactic, ana m eji ọgwụ eme ihe n'ụdị mbadamba.
Andrei 37 dị afọ iri atọ, Astrakhan: “Na nso nso a ha malitere ichegbu onwe ha gbasara itching na ihe mgbu na mpaghara akwara. Mgbe atọrọ dọkịta ahụ, ọ chọpụtara na m nwere radicular neuritis .. Ọkachasị akwara na-ahụ maka injebion nke Neurobion. Emere 1 ampoule kwa izu. Enwere m afọ ojuju n'ihi ọgwụgwọ a. "
Sabina dị afọ 30, Moscow: “M na-a vitaminsụ vitamin maka lumbar neuralgia ruo ogologo oge. Mgbe oge ụfọdụ gasịrị, ha kwụsịrị inyere aka. Mgbe m gakwuru dọkịta, ọ gwọrọ Neurobion. ọgwụ n’ụdị mbadamba ihe. ”
Artyom gbara afọ 25, Bryansk: “O jiri ọgwụ vitamin mee ihe n'ịgwọ ọrịa neuro-brachial syndrome. Gave nyere ọgwụ injots kwa ụbọchị ruo ụbọchị 5. druggwọ ọgwụ ahụ kwụsịrị mgbu mgbu ma mejupụtakwa anụ ahụ yana ọnụọgụ vitamin dị mkpa. Ejiri iji ọgwụgwọ mmezi gbochie nlọghachi. "