Metformin bụ ọgwụ ọgwụ eji eme ka ọdalata ọbara shuga n'ụdị shuga nke abụọ. Ọgwụ a nwere ọtụtụ uru ndị ọzọ. Dịka ọmụmaatụ, a na-eji ya maka ịdị arọ na ụfọdụ ọmụmụ na-egosi na ịdị irè ya na ọgwụgwọ ndị ọrịa cancer.
International Nonproprietary Aha
Aha njirimara nke ọgwụ a bụ Metformin (Metformin).
Metformin bụ ọgwụ ọgwụ eji eme ka ọdalata ọbara shuga n'ụdị shuga nke abụọ.
ATX
Koodu bu A10BA02. Ọgwụ na-emetụta usoro nri nri na metabolism, bụ ụzọ maka ọgwụgwọ maka ọrịa shuga. Ejiri ya ọgwụ hypoglycemic, ewezuga insulin. Biguanide.
Ha weputara udi ya na ihe mebere ya
A na-ere Metformin Long Canon na mbadamba. Ihe mejupụtara ya gụnyere 500/850/1000/2000 mg nke metformin.
Omume ọgwụ
Metformin nwere ihe dị iche iche na-enye ohere iji ya na ọgwụgwọ nke ọrịa ụfọdụ.
Ọgwụ yana igbochi ụdị shuga 2
Metformin na-ebelata ọkwa nke glycemia, si otú a na-echebe akụkụ ahụ na mmebi na-adịgide adịgide, nke nwere ike ibute dysfunction ma ọ bụ malfunction ha mgbe obere oge. Ọgwụ a na-arụ ọrụ site na nsonaazụ ya na AMPK, nke na-akpali nnabata nke glucose site n'ọbara banye na akwara. Metformin na-abawanye AMPK, nke na-eme ka akwara nwee ike iji glucose na-emekwu ihe, nke na-ebelata ịba ụba shuga n'ime ọbara.
Na mgbakwunye, metformin nwere ike belata glucose ọbara site na igbochi ihe o mepụtara (gluconeogenesis).
Mmụba insulin na-abawanye
Nchịkwa insulin bụ ihe na-akpata mmepe nke ụdị ọrịa shuga 2 nke ọrịa mellitus, mana a na-ahụkwa ya na ọrịa polycystic ovary syndrome nakwa dịka mmetụta n'akụkụ ọgwụgwọ HIV.
Ọgwụ na-abawanye uche insulin ma na-eme ka mmetụta insulin na-enwe n’ahụ́ belata ndị nwere ọrịa shuga.
Ọgụ mgbaàmà nke PCOS
Polycystic Ovary Syndrome (PCOS) bụ nsogbu homonụ nke na-ebutekarị oke ibu na iguzogide insulin. Metformin na - egbochi oke osụ, ọria aghara, na insulin n'ahụ. Na-eme ka ohere ịmụmụ nke ihe ịga nke ọma belata ohere nke ime ọpụpụ. Na-ebelata ohere nke ọrịa shuga na ọrịa mmegharị na ọrịa metụtara akwara polycystic.
Metformin na - ebute ohere ime nke ọma ma belata ohere ime ọpụpụ.
Nwere ike igbochi kansa ma ọ bụ jiri ya na ọgwụgwọ ya
Metformin kwụsịrị uto na ụdị ọrịa kansa ụfọdụ n’ime ihe karịrị ndị ọrịa 300,000 nwere ọrịa shuga 2.
Nyocha meta meta kpughere mbelata 60% na ọrịa cancer nke imeju (intrahepatic cholangiocarcinoma) n'ime ndị nwere ọrịa shuga bụ ndị edepụtara ọgwụ metformin. Ọmụmụ ihe ahụ gosipụtara mbelata nke ahụike nke ọrịa palọ na ara ure, ọrịa ụkwara nta na ọrịa akpa ume site na 50-85%.
Kedu ọdịiche dị n'etiti Amoxiclav na Flemoxin Solutab?
Kiwi bara uru maka ndị ọrịa mamịrị? Gụkwuo na akụkọ ahụ.
Ntuziaka maka iji Detralex 1000.
Na-echebe obi
Ọtụtụ mgbe, otu n'ime ihe kacha akpata nsogbu nke ịmalite ọrịa obi bụ enweghị atụ na glucose ọbara.
Nnyocha nke ndị ọrịa 645,000 nwere ọrịa shuga gosipụtara ike nke metformin iji belata ọrịa obi (ọnya fibrillation).
Lowers cholesterol
Metformin lolesterol dị “njọ”, lipoproteins dị ala (LDL).
Na-atụnye ụtụ n'ibelata ibu
N'ime nnyocha e mere na ụmụ nwanyị nọ n'etiti afọ nwere nnukwu insulin n'ihe metụtara shuga ọbara na oke ahụ, a chọpụtara na metformin na - enyere aka belata ibu.
N'ọmụmụ ihe ọzọ, metformin belatara usoro ndekọta ahụ mmadụ na mmadụ 19 bu nje oria HIV na nkesa oke abụba (lipodystrophy).
Nwere ike ịgwọ ọrịa nrụrụ nwoke
Ọtụtụ nnyocha egosila na metformin nwere ike belata nrụrụ nke nwoke na oke ibu, insulin na-egbochi ma ọ bụ ọrịa shuga.
Nwere ike chebe mmebi nke Gentamicin kpatara
Gentamicin bụ ọgwụ nje na-emebi mmebi akụrụ na auditory system. Metformin nwere ike ichebe oke ịnụ ntị nke ihe na-akpata site na ịbanye na Gentamicin.
Ọgwụ nke ọrịa imeju na-adịghị egbu egbu
NAFLD bụ ọrịa imeju na-adịghị ala ala nke na -eme ụmụ irighiri abụba na-emetụta imeju, mana nke a adịghị emetụta ị alcoholụ mmanya. Metformin na --ebelata mmetụ nke mkpokọba abụba.
Mlọ ọgwụ
Nke zuru ezu site na eriri afọ ma ọ bụ nke na-achịkwa mmụọ. Bioavailability dị 60%. Na plasma, a na-ahụ ọdịnaya kachasị na elekere 2.5 gachara.
Ọ na-abụpụtara onwe ya site na akụrụ na-agbanweghi.
Ihe ngosi maka ojiji
Ndị ọrịa nwere ụdị ọrịa shuga 2 nke ọrịa mellitus (nke kachasị maka ndị buru ibu) dị ka monotherapy ma ọ bụrụ na enweghị nsonaazụ a na-ahụ anya site na nri kwesịrị ekwesị na mmega ahụ. Edere ya na ọgwụ ndị nwere mmetụta hypoglycemic, ma ọ bụ insulin.
Ihe ngbanwe
Ọ contraindicated na ndị ọrịa na ndị na-esonụ ikpe:
- hypersensitivity na ihe na-arụ ọrụ;
- nsogbu akụrụ;
- acidosis na-adịghị ala ala, gụnyere ketoaciadiasis na-arịa ọrịa shuga (na ma ọ bụ na-enweghị coma), nnukwu infarction myocardial;
- arụ ọrụ akụrụngwa ma ọ bụ ọria ọria;
- lactic acidosis;
- ọrịa ndị nwere ike iso kpata ọrịa hypoxia anụ ahụ;
- afọ ime, oge inye ara;
- afọ ruo afọ 18.
Jiri nlezianya
Ejiri ogwu mee ka ogwu juo ndi oria mara agadi ndi n’eme aru aru ike.
Uzo esi ewere Metformin 1000
Edere ya ọnụ. Onye dọkịta na-ahụ maka ịga n'ihu na-enye usoro ọgwụgwọ ahụ kwa ụbọchị.
Tupu ma ọ bụ mgbe nri
A na-ewere ọgwụ a n'oge nri ma ọ bụ ozugbo nri.
Na-arịa ọrịa shuga
Mgbe ụfọdụ, ejikọtara ya na insulin. Ọ bụ dibịa na-eleta anya nyere ndụmọdụ nke nkọwapụta.
Maka ịdị felata
Ekwenyere na ọgwụ a nwere ike inye aka maka oke ibu. Ma, tupu iji ya, a chọrọ ndụmọdụ ọkachamara.
Nsonaazụ nke Metformin 1000
Ohere nwere ike ịpụta:
- lactic acidosis, nke na-eduga na mgbu mgbu, ike ọgwụgwụ, akpata oyi, ọgbụgbọ, ura;
- uto ọla n’onu;
- wedata ọbara mgbali elu;
- hypoglycemia;
- agụụ.
Ọkpụkpụ afọ
O nwere ike ibute ọgbụgbọ, vomiting, anorexia, afọ ọsịsa, akpịrị akụrụ, flatulence.
Site n'akụkụ nke metabolism
Na-adịkarị ala na-akpata lactic acidosis.
Na anụahụ
Ọdịdị nke ọnya, ọnya afọ.
Usoro endocrine
Enwere ike ịba ọcha n'anya.
Ahụhụ
Mmeghachi omume nfụkasị ahụ ga-ekwe omume.
Mmetụta ikike ịchịkwa usoro
Ọ bụrụ naanị na a drugụrụ ọgwụ a, mgbe ahụ enweghị mmetụta ọ bụla. Mgbe ị usedụ ọgwụ antidiabetic, a na-atụ aro ka ị zere ihe omume chọrọ nlebara anya.
Ntụziaka pụrụ iche
Enweghi ike iji ọgwụ ahụ ụbọchị 2 tupu ịwa ahụ yana awa 48 mgbe ọ nwesịrị ya (ọ bụrụhaala na onye ọrịa nwere ọrụ akụrụ nkịtị).
A na-atụ aro ka emee ya mgbe nile iji chịkwaa ọrịa shuga.
Tupu ojiji, ọ bara uru ịgụ ntuziaka maka ojiji.
Jiri n'oge ime na lactation
Iji n'oge ime bụ adịghị anabata. N'oge usoro ọgwụgwọ, a ga-akwụsịtụ inye ụmụ ya ara.
Cribdebe Metformin na ụmụ 1000
Edere ọgwụ ahụ ka ndị ọrịa malite n’afọ 18 gboo.
Jiri na agadi
Mgbe ị na-ede akwụkwọ maka ndị ọrịa agadi, ọ dị mkpa ileba anya na steeti ahụ ike.
Ngwa maka ọrụ ezughi oke ọrụ
Agaghị atụ aro.
Jiri maka ọrụ imeju na-arụ ọrụ
Agaghị atụ aro.
Ndopu nke Metformin 1000
Bụrụ na ị doụbiga ihe ọdoụdoụ ókè, iwepụ mmetụta nke mmetụta na-adị njọ.
Ọ bụrụ na ị gafere ogo ahụ, gakwuru dọkịta ozugbo.
Mmekọrịta na ọgwụ ndị ọzọ
Ejikọtara ya na ndị na-ejide iodine nwere rediopaque.
Mgbe ejikọtara ya na danazol, chlorpromazine, glucocorticosteroids, diuretics, injections beta2-adrenergic, ịkpachara anya na itinyekwu glucose ọbara n'ọtụtụ oge.
A machibidoro ya ijikọta metformin na ọgwụ iodine nwere ọgwụ rediopaque.
Mgbe ejiri ọgwụ antidiabetic mee ihe, igosipụta hypoglycemia kwere omume.
Lelee maka ndakọrịta ọgwụ niile ị na-a takeụ n'oge ọgwụgwọ ya na metformin.
Mmanya ndakọrịta
Ekwesighi ijikọ ya na mmanya mmanya, dịka enwere ike ịbanye lactic acidosis na-abawanye.
Analogs
Ọ bụrụ na achọrọ, enwere ike iji analogues ndị a kama iji Metformin:
- Siofor;
- Glycometer;
- Metformin Richter;
- Metformin-Teva;
- Diaformin;
- Glucophage;
- Insufor na ndi ozo
Ahịa ọgwụ na-ahapụ okwu
Ire ere ọgwụ Metformin 1000 (na Latin - Metforminum) bụ ọgwụ.
Enwere m ike ịzụta na ndenye ọgwụ
Na Russia, ire ịre ọgwụ ọgwụ mgbe enweghị ọgwụ ọgbo.
Ọnụ ego maka Metformin 1000
Ọnụ ego ọgwụ a na-ere ọgwụ na Russia na-adị iche site na 190 ruo 250 rubles.
Ọnọdụ nchekwa maka ọgwụ
Ọ na-atụ aro ịchekwa ọgwụ a na okpomọkụ agaghị akarị + 25 Celsius C n'ebe gbara ọchịchịrị na ala akọrọ nke ụmụaka adịghị enweta.
Bọchị mmebi
Afọ 3
Emeputa
LLC "comlọ Ọrụ Nkesa Nycomed" (Russia, Moscow).
Nyocha banyere Metformin 1000
Ndị ọkachamara kwadoro ngwa a maka ọgwụgwọ nke ọrịa dị iche iche.
Ndi dibia
Bobkov E.V., onye na-ahụ maka izugbe, dị afọ 45, Ufa: "Ọgwụ siri ike nke a na-eji agwọ ọrịa shuga dị afọ 2."
Danilov S.P., onye na-ahụ maka izugbe, 34 afọ, Kazan: "N'ime afọ ndị gafeworonọ, ọ gosipụtara arụmọrụ ya n'ọgụ megide oke ibu. Ọ na - enyere aka inweta ezigbo mmetụta n'oge obere oge."
Ndị ọrịa
Dmitry, onye gbara afọ 43, Vladivostok: "Ana m arịa ọrịa shuga 2. Ana m a medicineụ ọgwụ na injections insulin ihe dị ka otu afọ. Ọ na-ebelata glucose ọbara."
Vladimir, onye dị afọ 39, Ekaterinburg: "Ewere m Glibenclamide ogologo oge, ma mgbe e mesịrị Metformin ka edepụtara ya. A na-ebugharị ya n'ụzọ dị mma, na ọbara ọbara m laghachiri na nkịtị, ọnọdụ m bịara dị mma."
Ibelata ibu
Svetlana, dị afọ 37, Rostov-on-Don: "Azụtara m ọgwụ a na ndụmọdụ nke onye na-ahụ maka nri na-edozi ahụ. Ahụghị m mmetụta dị mma."
Valeria, onye gbara afọ 33, Orenburg: "Kemgbe ọ bụ nwata, ọ na-adịkarị njọ. Onye dibia bekee gwara Metformin. Otu ọnwa ka ọ kwụsịrị, ọ kwụsịrị ị itụ ya, n'ihi na ọ bụ onye nzuzu na onye nzuzu."
