Ihe na-ebutekarị ọrịa obi bụ ọbara mgbali elu akwara, nke a na-egosipụta n'ọbara dị elu. Nke a na-ebelata ịdị mma nke ndụ mmadụ. Ndị ọkachamara na-atụ aro ị toụ ọgwụ dịgasị iche iche antihypertensive na-egbochi homonụ oligopeptide (angiotensins) nke na-akpata vasoconstriction. Ọgwụ ndị a gụnyere Lorista ma ọ bụ Losartan.
Kedu ka ọgwụ ndị a si arụ ọrụ?
Ọbara mgbali elu nwere ike ibute mgbanwe mgbanwe na mgbidi nke akwara ọbara n'ahụ niile. Nke a dị oke egwu maka obi, ụbụrụ, retina na akụrụ. Akụkụ ike na - arụ ọrụ nke ọgwụ abụọ a (losartan potassium) na - egbochi angiotensins, na - akpata vasoconstriction na mmụba dị elu, na - ebute mgbapụta nke homonụ ndị ọzọ (aldosterones) site na adrenal gland n'ime n'ọbara.
Lorista ma ọ bụ Losartan bụ ọgwụ ndị na - egbochi ihe mgbochi na - egbochi homonụ oregopeptide (angiotensins) na - akpata vasoconstriction.
N'okpuru nduzi nke aldosterone:
- reabsorption (absorption) nke sodium na-abawanye na ya na-egbu oge na ahụ (Na na-akwalite hydration, na-etinye aka na mpụta nke ngwaahịa metabolic na ngwaahịa, na-enye ntụpọ alkaline nke plasma ọbara);
- N-ion na ammonium gabigara;
- n'ime ahụ, a na-ebugharị chlorides n'ime sel ma na-enyere aka izere akpịrị ịkpọ nkụ;
- olu nke mgbasa ọbara;
- a na-ahazi acid-base balance.
Lorista
A na-eme ọgwụ antihypertensive n'ụdị mbadamba mkpụrụ osisi, nke gụnyere potassium losartan, yana ihe ndị ọzọ:
- cellactose;
- silikon dioxide (sorbent);
- steeti magnesium (ihe mgbochi);
- microtized gelatinized ọka stachi;
- hydrochlorothiazide (ihe na-eme ka ọ bụrụ ihe agbadoro iji chebe ọrụ akụrụ achọtara analogues nke Lorista, dịka Lorista H na ND).
Dị ka akụkụ nke mpụga shei:
- ihe nchebe hypromellose (ihe dị nro);
- plasticizer propylene;
- dyes - quinoline (E104 odo) na dioxide titanium (E171 ọcha);
- ntụ ntụ talcum.
Kedu ihe achicha achicha eji eme ya maka ndi oria shuga?
Cardioactive Taurine: ihe ngosi na contraindications nye ogwu.
Gụọ banyere isi ihe kpatara ọrịa shuga n’isiokwu a.
Ihe na-arụ ọrụ, na-egbochi angiotensin, na-eme ka akwara vaskụla ghara ikwe omume. Nke a na - enyere aka idozi nrụgide. Losartan kenyere:
- na mgbaàmà mbụ nke ọbara mgbali elu na monotherapy;
- ya na obara mgbali elu n’ulo ogwu a gwakọtara;
- ọrịa shuga.
A na-emepụta Lorista na 12.5, 25, 50 na 100 mg nke isi ihe na 1 mbadamba. Nchịkọta na 30, 60 na 90 PC. na ngwugwu. N'ime ọkwa mbụ nke ọbara mgbali elu, a na-edenye 12.5 ma ọ bụ 25 mg kwa ụbọchị. Site na mmụba na ọkwa ọbara mgbali elu, oriri na-abawanye. Ekwesịrị ka ekwenyere ndị dọkịta na-aga elele oge a ga -eche ya.
Lorista na-arụ ọrụ na-egbochi angiotensin na - eme ka nsụchi akwara ghara ikwe omume. Nke a na - enyere aka idozi nrụgide.
Losartan
A na-ewere ọnụ na ọnụ ma nwee 25, 50 ma ọ bụ 100 mg nke ihe ndị bụ isi na ihe ndị ọzọ na mbadamba 1:
- lactose (polysaccharide);
- cellulose (eriri);
- silikon dioxide (emulsifier na mgbakwunye nri) E551);
- magnesium stearate (emulsifier E572);
- ssummasị croscarmellose (ihe mgbaze nri);
- povidone (enterosorbent);
- hydrochlorothiazide (na nkwadebe nke Lozartan N Richter na Lozortan Teva).
Ihe mkpuchi ihe nkiri na-agụnye:
- ọgugu emeli nke eze;
- dyes (ọcha titanium dioxide, odo iron oxide);
- macrogol 4000 (na-abawanye oke mmiri n’ime ahụ);
- ntụ ntụ talcum.
Losartan, na-egbochi angiotensin, na-enyere aka weghachi ọrụ nkịtị nke akụkụ ahụ niile:
- anaghị emetụta ihe ọkụkụ;
- anaghị akpata vasoconstriction (vasoconstriction);
- na-ebelata nguzogide nke ha;
- na - achịkwa nrụgide na aorta na okirikiri nke mgbasa ọbara;
- na-ebelata ọbara mgbali myocardial;
- na -eme ka ụda dị na arịa ụkwara;
- na-arụ ọrụ dịka diuretic;
- oge dị iche na oge ọrụ (ihe karịrị otu ụbọchị).
A na-enweta ọgwụ ahụ ngwa ngwa site na nri diges, metabolized n'ime sel imeju, ihe kachasị na ọbara na-apụta mgbe otu elekere gasịrị, na-ejikọ protein protein 95% nke metabolite na-arụ ọrụ. Losartan na - apụta na mmamịrị (35%) na bile (60%). Usoro inwere ike ịnabata doti ruru 200 mg kwa ụbọchị (kewara abụọ.)
Losartan, na-egbochi angiotensin, na-enyere aka weghachi ọrụ nkịtị nke akụkụ ahụ niile.
Tụnyere nke Lorista na Losartan
Ebumnuche nke ọgwụ abụọ ahụ bụ iji belata nrụgide. A na-edenyekarị ndị ọrịa hypertensive, ebe ọ bụ na achọpụtara mmetụta dị mma ma na mgbochi nke ọrịa obi na ọrịa vaskụla, yana dịka ọgwụgwọ bụ isi maka ọnọdụ adịghị ala ala. Ogwu adighi adighi ebute nsogbu, nwere otutu ihe omuma ya na obere odi iche.
Mmekorita
Ekwuputala ịdị irè nke ọgwụ ndị ahụ maka ndị ọrịa na-arịa ọbara mgbali elu, yana ihe ndị dị ize ndụ dị ka:
- ịka nká;
- bradycardia;
- mgbanwe mgbanwe akwara na aka ekpe ventricular myocardium nke tachycardia kpatara;
- nkụchi obi;
- oge mgbe nkụchi obi.
Ọgwụ ndị sitere na potassium losartan dabara adaba na nke ahụ:
- tinye oge 1 kwa ụbọchị (ma ọ bụ karịa, ma dị ka onye ọkachamara nyere iwu);
- nnabata anaghị adabere na nri;
- ihe nọ n'ọrụ nwere mmetụta ngụkọta;
- ụzọ kachasị mma si otu izu rue otu ọnwa.
Ọgwụ nwere otu contraindications:
- nfụkasị na mmiri;
- hypotension;
- afọ ime (nwere ike ibute ọnwụ nwa ebu n'afọ);
- oge lactation;
- afọ ruru afọ 18 (n'ihi eziokwu ahụ na nsonaazụ ụmụaka anaghị aghọtacha);
- ọnya ọria-ụlo.
Maka ndị ọrịa nwere nsogbu gbasara akụrụ, ọgwụ adịghị contraindicated ma enwere ike ịkọ ya ma ọ bụrụ na enwere hydrochlorothiazide na mejupụtara, nke:
- na - eme ka ọbawanye ọbara nke akwara;
- akpata mmetụta nephroprotective;
- eme ka ntụpọ urea dị mma;
- Na-enyere aka belata mmalite nke gout.
Kedu ihe dị iche?
Esemokwu dị iche iche dị n'etiti ngwaọrụ ndị a bụ nke ego na onye nrụpụta kpebiri. Lorista bụ ngwaahịa nke ụlọ ọrụ Slovenian KRKA (Lorista N na Lorista ND bụ Slovenia mepụtara ya na Russia). Site na nyocha nke ọkachamara, nnukwu ụlọ ọrụ na-ere ọgwụ nwere aha n'ahịa mba ụwa na-ekwe nkwa ịdị mma nke ọgwụ.
A na-emepụta Losartan na Ukraine site na Vertex (Losartan Richter - Hungary, Losartan Teva - Israel). Nke a bụ analegori nke Lorista dị ọnụ ala karịa, nke na-apụtaghị na ọ bụ agwa ka njọ ma ọ bụ na-adịchaghị mma. Ọkachamara ndị na-ede ọgwụ a ma ọ bụ ọgwụ ahụ, kwuru ụfọdụ ọdịiche, gụnyere nsonaazụ ya.
Mgbe ị na-etinye Lorista:
- na 1% nke ikpe, a na-akpata arrhythmia;
- A na-ahụta ngosipụta, na - akpasu iwe site na diuretic hydrochlorothiazide (ọnwụ nke potassium na sodium salts, anuria, gout, proteinuria).
A kwenyere na losartan dị mfe ibu, mana adịkarịghị eduga na:
- n'ime pasent 2 nke ndị ọrịa - na mmepe nke afọ ọsịsa (akụkụ macrogol bụ ihe mkpali);
- 1% - ka myopathy (mgbu na azụ na akwara na mmepe nke uru ahụ).
N'ọnọdụ ndị na-adịghị ahụkebe, losartan nwere ike imetụta mmepe nke afọ ọsịsa.
Kedu nke dị ọnụ ala?
Costgwọ ahụ na-emetụta ihe dịka mpaghara obodo ahụ, nkwalite na mbelata ego, ọnụọgụ na olu ụdị mbipụta ahụ chọrọ.
Ego Lorista:
- 30 PC 12.5 mg nke ọ bụla - 113-152 rubles. (Lorista N - 220 rubles.);
- 30 PC 25 mg nke ọ bụla - 158-211 rubles. (Lorista N - 302 rubles, Lorista ND - 372 rubles);
- 60 pcs. 25 mg nke ọ bụla - 160-245 rubles. (Lorista ND - 570 rubles);
- 30 PC 50 mg nke ọ bụla - 161-280 rubles. (Lorista N - 330 rubles);
- 60 pcs. 50 mg nke ọ bụla - 284-353 rubles;
- 90 PC 50 mg nke ọ bụla - 386-491 rubles;
- 30 PC 100 mg nke ọ bụla - 270-330 rubles;
- 60 taabụ. 100 mg - 450-540 rubles;
- 90 PC 100 mg nke ọ bụla - 593-667 rubles.
Akwụ ụgwọ nke losartan:
- 30 PC 25 mg nke ọ bụla - 74-80 rubles. (Losartan N Richter) - 310 rubles .;
- 30 PC 50 mg nke ọ bụla - 87-102 rubles;
- 60 pcs. 50 mg nke ọ bụla - 110-157 rubles;
- 30 PC 100 mg - 120 -138 rubles;
- 90 PC 100 mg nke ọ bụla - ihe ruru 400 rubles.
Site na usoro ndị a dị n'elu o doro anya na ọ bara uru karị ịzụta losartan ma ọ bụ ọgwụ ọ bụla, mana enwere nnukwu mbadamba mbadamba.
Kedu ihe dị mma lorista ma ọ bụ losartan?
Kedu ọgwụ ka mma, ọ gaghị ekwe omume ịsị na enweghị nkwekọrịta, ebe ọ bụ na ha dabere na otu ihe ahụ na-arụ ọrụ. Dọkịta na-aga ya ga-akpali nke a, dabere n'ụkpụrụ onye ọrịa ahụ nwere. Mana mgbe ejiri ya, ekwesịrị ibute nsonaazụ nke ihe ndị ọzọ etinyere na nhazi ahụ.
N'ihi eziokwu ahụ bụ na Lorista na-ewere obere usoro onunu (12.5 mg), etinyere ya maka igbochi ọnọdụ ọbara mgbali elu, ọnụnọ nke ọrịa obi na-adịghị ala ala, n'ọnọdụ nke mgbanwe mgbanwe spasmodic na ọkwa nke nrụgide. N'ezie, enwere ike ịrịa hypotension a na-achịkwaghị achịkwa, nke dịkwa ize ndụ nye onye ọrịa, ebe ọ bụ na mgbaàmà ya anaghị apụta ozugbo. Ọbara mgbali elu mara oke elu na mbelata ọbara mgbali elu nwere ike ịchịkwa obere ọgwụ a takenụrụ ugboro abụọ.
Nyocha nyocha Ndidi
Olga, 56 afọ, Podolsk
Enweghị m ike ị takeụ ọgwụ ndị a nke dọkịta na-enye m iwu. M dụọ mmiri kwa ụbọchị nke 50 mg nke losartan. Otu ọnwa mgbe nke a gasịrị, ọbara na-apụ apụ n'aka (na-egbu ma daa na aka). Askorutin kwụsịrị ị itụ ya wee malite ị drinkụ mmiri, dị ka a ga - asị na ọnọdụ arịa ndị ahụ emebiela. Mana nrụgide ahụ na-adịgide. Afere ya na Lorista dị ọnụ ala karịa. Mgbe oge ụfọdụ gasịrị, ihe niile emeghachiri. Agụrụ m na ntuziaka - enwere mmetụta dị n'akụkụ a. Kpachara anya!
Margarita, afọ 65, obodo Tambov
Edere ya Lorista, mana gbanwere onwe ya na Losartan. Kedu ihe kpatara ịkwụ ụgwọ maka ọgwụ nwere otu ihe eji eme ihe?
Nina, 40 afọ, Murmansk
Ọbara mgbali elu bụ ọrịa nke narị afọ. Nchegbu na-arụ ọrụ na n'ụlọ n'oge ọgbọ ọ bụla na-ebute nrụgide. Ha gwara Lorista ka ụzọ dị mma ọ dị, mana na nkọwapụta banyere ọgwụ ahụ enwere ọtụtụ contraindications. Mgbe m gụchara ntuziaka ahụ, ekpebiri m ịga hụ dọkịta ọzọ.
Ime ime bu igbochi ọgwụ ojoo.
Nyocha nke ndị ọkachamara n'ọrịa obi na Lorista na Losartan
M.S. Kolganov, dibia bekee, Moscow
Ego ndị a nwere ọghọm dị na otu nke ndị na-egbochi angiotensin. Ha na-ekwu n'eziokwu ahụ na mmetụta ahụ na-apụta nwayọ, yabụ enweghị ụzọ ọ bụla iji gwọọ mgbali elu nke akwara ngwa ngwa.
S.K. Sapunov, dibia ukwu, Kimry
N'ime ihe mejupụtara nke angiotensin niile na - egbochi ụdị nke abụọ, naanị Losartan na - ezute akara 4 maka iji rụọ ọrụ: ọbara mgbali elu; ọbara mgbali elu n'ihi ọbara mgbali elu ventricular; ụdị 2 ọrịa nephropathy na-akpata; ike ọgwụgwụ nke obi.
T.V. Mironova, dibia bekee, Irkutsk
Erere ọgwụ ndị a na - arụgide ọrụ na - edozi ọnọdụ ahụ ma ọ bụrụ na a na - ewere ya n'ihu. Site na usoro ọgwụgwọ ezubere, a ga-ebelata ohere nke ọdụdọ. Ma, na nnukwu ala ha anaghị enyere aka. Na-ere ọgwụ.
