R-lipoic acid (aha ndị ọzọ - lipoic, alpha-lipoic ma ọ bụ thioctic acid) bụ ọgwụ antioxidant sitere na ihe na - egbochi ụbụrụ, na - enyere aka n'ibu oke, na - eme ka ọrịa shuga na - ebelata ihe ize ndụ nke ọrịa obi ma na - eme ka ahụ pụọ. mgbu Ma ndị a bụ ụfọdụ n'ime ọtụtụ uru nke "antioxidant ụwa a nile."
International Nonproprietary Aha
Thioctic acid.
Thioctic acid bụ ihe antioxidant sitere n'okike na mgbochi mkpali.
ATX
Na nkewa, ATX nwere koodu A16AX01. Nke a pụtara na a na-eji ọgwụ a agwọ ọrịa nke imeju ma melite metabolism.
Weputara udi ya na ihe mebere ya
Ọ dị n'ụdị mbadamba, mbadamba iri ise n'otu mkpọ. Ihe dị n’ime ihe dị n’ime bụ 12 mg ma ọ bụ 25 mg. A nwekwara ike ịchọta acid a na capsules yana dịka ihe ngwọta maka injection.
Omume ọgwụ
Lipoic acid bụ obere ihe na-enweghị protein na-agwakọta n'ụzọ pụrụ iche na protein ndị kwekọrọ. Acid a na-arụ ọrụ dị mkpa na nguzo ike nke anụ ahụ. Site na echiche nke mmiri ọgwụ, mmetụta ya yiri nke a na-eme na vitamin B Ọ na-eme ka ọrụ imeju ka mma, bụ ihe na-eme ka mmiri ọgwụ na-egbu egbu ma ọ bụ nnu dị arọ na mmịrị ndị ọzọ.
Mlọ ọgwụ
Bioavailability bụ 30%. Kesara na olu nke 450 ml / n'arọ. 80-90% akụrụ wepụrụ.
Lipoic acid bụ obere ihe na-enweghị protein na-agwakọta n'ụzọ pụrụ iche na protein ndị kwekọrọ.
Ihe ngosi maka ojiji
Alfa lipoic acid nwere ọtụtụ ihe bara uru ị nwere ike iji. Imirikiti ihe ndị na-agwọ ọrịa bụ n'ihi eziokwu na acid a bụ antioxidant.
A na-akwalite ọkwa nke homonụ nke thyroid gland na-emepụta
Ọ bụrụ na ahụike nke thyroid gland na-emebi emebi, mgbe ahụ ntọhapụ nke homonụ na-apụtaghị. Ọmụmụ ihe ọmụmụ nke 2016 chọpụtara na alfa lipoic acid nke a na-eji quercetin na resveratrol nyere aka mee ka ọkwa hormone dị mma.
Na-akwado Ahụike Ọrịa
Y’oburu na odi malu na sistemu nsogbu, mgbe ahu tinging ma obu ntughari nwere ike ime. Nke a nwere ike igbochi nhazi mmadu na ikike ijide ihe. Ka oge na-aga, nke a nwere ike ịba n’ihu ma kpatara ọtụtụ nsogbu. Nnyocha e mere egosiwo na acid a nwere ike ịkwado ahụike nke sistem ahụ, ọkachasị na njeri ya.
Na-akwado Ọrụ Cardio
Studiesfọdụ nnyocha gosiri na thioctic acid na-echebe sel akwara ma na-enwe ahụike ha. Acid a na - emekwa ka ọ dịrị n’iru ọbara, na-enye aka eme ka ahụike dịrị n’obi.
Na - egbochi mọzụlụ site na nrụgide sitere na mmega ahụ
Worfọdụ mgbatị ahụ nwere ike ime ka arụmọrụ arụ dị ngwa na anụ ahụ, nke na-emetụta oke anụ ahụ na akwara, ikekwe ihe mgbu. Nri ndi nwere ihe nke antioxidant, dika R-lipoic acid, nwere ike belata uto a.
Na-akwado ọrụ imeju
Ọtụtụ nnyocha na-egosi na acid a na-enye aka na ọrụ imeju na-arụ ọrụ nke ọma ma na-enyere aka ịnagide mmachi nke ahụ.
Additional Anụ ọgwụ ọzọ nwere ike ime ka ncheta dịkwuo mma.
Na-ewusi ebe nchekwa ma na-akwado ahụike ụbụrụ
Ka mmadụ dịkwuo afọ, a na-emepụta obere lipoic acid n’ahụ. Nchebe megide radicals na-esighi ike. Nke a nwere ike ibute mmebi nke akpịrị. Na mgbakwunye na ọgwụ a nwere ike ịkwalite ebe nchekwa na ahụike ụbụrụ n'ozuzu ya.
Na-akwalite Ahụ Ike
Alfa lipoic acid nwere ike inyere ndị nkụ aka, na-ewe iwe, ma ọ bụ nwee anụ ahụ.
Na-eme ka usoro ịka nká dị.
Ka afọ ndụ anyị na-abawanye, ihe a na - egbochi oxidative na - abawanye ma na - abawanye sel sel nke ahụ anyị. Nnyocha e mere egosiwo na ọgwụ a nwere ike inye aka mee ka usoro a dị mma, gbue mmalite nke ọrịa ndị metụtara ọrụ obi, chebe ụbụrụ site na ọrịa ndị metụtara ọrịa dementia.
Na-akwado glucose Ọbara
Obere insulin ala n’enwe ike ibute nsogbu ahu ike n’ihi nnukwute glucose na ọbara. Nchọpụta emere nwapụta na thioctic acid na - enyere aka ịlụ ọgụ ịbawanye n'ọbara shuga.
Na-akwado Ike Ahụike
Iji weghachite ịdị arọ gị na nkịtị, ịchọrọ mmega ahụ oge niile, nri kwesịrị ekwesị. Ihe mgbakwunye dị ka alfa lipoic acid nwere ike ịbawanye mmetụta nke ndụ ahụike na ahụ mmadụ.
Ihe ngbanwe
Enweghị ọtụtụ contraindications maka usọ a. Ndị a gụnyere ime, lactation, na ụfọdụ nsogbu ụbụrụ. Enwere obere data maka mmetụta ọgwụ nwere n'ahụ ahụ ụmụaka. Site na hypersensitivity na mmiri nke ọgwụ ahụ, a machibidoro iji ya.
Etu esi ewere R-lipoic acid
Ọ dị n'ụdị mbadamba, capsules ma ọ bụ ntụtụ. Mbadamba na capsules ka a na-eji nri ma ọ bụ na-eji mmiri buru ibu, a na-ejikwa mmiri ahụ agwọ ọrịa.
Tupu ịmalite iri nri
A na-atụ aro iji nri ma ọ bụ jiri mmiri buru ibu.
Na-arịa ọrịa shuga
Enwere ike inye ndị na-ahụ maka ịga ọgwụ ndụmọdụ maka iji acid na ụdị ọrịa shuga mellitus 1 na nke 2.
Nsonaazụ R-lipoic acid
Na usoro onunu ogwu, ọ naghị emetụta ya n'ụzọ dị njọ. Nsonaazụ kachasị emetụta: itching, ihe ngbu, mmeghachi omume nfụkasị ọzọ na ọgbụgbọ, mgbu afọ.
Enwere ike inye ndị na-ahụ maka ịga ọgwụ ndụmọdụ maka iji acid na ụdị ọrịa shuga mellitus 1 na nke 2.
Mmetụta ikike ịchịkwa usoro
Amachibido ịkwọ ụgbọ ala, mana n'ihi ọgbụgbọ na ọnya afọ, nke nwere ike ịmetụta ntị, a na-atụ aro ịkpachara anya.
Ntụziaka pụrụ iche
Tupu iji ọgwụ a, gakwuru ọkachamara.
Jiri na agadi
Ngwọta a nwere ike igbochi ụfọdụ nsogbu ahụike metụtara ịka nká.
Inye umuaka
Enwere obere nnyocha na ozi banyere mmetụta ọgwụ nwere n'ahụ ahụ ụmụaka, yabụ akwadoghị njikwa onwe onye maka ụmụaka. Dodoụbiga mmanya ókè na-a theụ ọgwụ ahụ na ihe karịrị 50 mg kwa 1 n'arọ nke ịdị arọ.
Jiri n'oge ime na lactation
Contraindicated.
Do Overụbiga Mfe nke R-Lipoic Acid
Bụrụ na ịdoụbiga ihe ọ ,ụ overụ ókè, mmetụta ya na-adịwanye njọ.
Enwere obere nnyocha na ozi banyere mmetụta ọgwụ nwere n'ahụ ahụ ụmụaka, yabụ akwadoghị njikwa onwe onye maka ụmụaka.
Mmekọrịta na ọgwụ ndị ọzọ
Na-eme ka mmetụta mgbochi mkpali nke glucocorticoids. Na-ebelata mmetụta nke cisplatin. Na-emekwa ka ịdị irè nke insulin na hypoglycemic na-arụ ọrụ.
Mmanya ndakọrịta
A na-eji ya mee ihe na mgbagwoju anya na ọgwụgwọ nke ịhoụbiga mmanya ókè.
Analogs
Analogues nke ọgwụ gụnyere:
- Thioctacid;
- Tiogammu;
- Espa lipon;
- R-alpha lipoic acid, biotin;
- Thiolipon na ndị ọzọ
Ahịa ọgwụ na-ahapụ okwu
Ọ dị enweghị ndenye ọgwụ.
Ọnụahịa
Ọnụ ego dị nso maka ọgwụ a:
- Lipoic acid, mbadamba 25 mg, 50 PC. - ihe dị ka ruble 50;
- Lipoic acid, mbadamba 12 mg, 50 PC. - ihe dị ka ru ru 15.
Ọnọdụ nchekwa maka ọgwụ
Ọnọdụ aga-ezute:
- ebe kpọrọ nkụ;
- enweghị ìhè;
- nchebe ụmụaka;
- okpomọkụ agaghị akarị 25 Celsius.
Bọchị mmebi
Afọ 3
Emeputa
Marbiopharm, Russia.
Nyocha
Ndi dibia
Iskorostinskaya O. A., ọkachamara n'ọrịa ụmụ nwanyị, Vladivostok: "Ngwọta zuru ụwa ọnụ na akụrụngwa antioxidant (dịka ọmụmaatụ, ọ na - egbochi ụdị oxygen dị iche iche), ọ nwere ezi uche oge niile iji na - ebute ndị ọrịa shuga."
Lisenkova O. A., akparamaagwa akwara, Novorossiysk: "Nnabata ọfụma na oke ọfụma n'ihe gbasara iji ya eme ya.
Ndị ọrịa
Alisa N., Saratov: "Ezigbo usọbọ. Ọ dị ọnụ ala, ma ọ dị irè. Akenweta oke ọgwụgwọ na-enweghị mmetụta ọ bụla ga-ekwe omume."
Svetlana Yu., Tyumen: “Ha nyere ọgwụ thioctic acid, were mbadamba mkpụrụ ọgwụ 1 kwa ụbọchị ruo ọnwa 2. Mmetụta agụụ na-apụ n'anya, enwere m mmetụta ọgwụ a mgbe niile.”
Ibelata ibu
Anastasia, Chelyabinsk: "Mgbe ọgwụ a gachara, enwere m mmetụta na-emeziwanye ahụike n'ozuzu ahụ. M ga-atụkwa kilogram 2-3 kwa oge. N'otu oge ahụ, ọnụahịa ahụ dị ọnụ ala."
Ekaterina, Astrakhan: "Mmetụta ahụ dị mma n'ezie. Ọnọdụ anụ ahụ adịla mma, ma ọdịda ntakịrị. Agbanyeghị, eji ọgwụ a achịkwaa oke n'ibelata oke."
