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A na-eji mbadamba amaryl mee ihe maka ịgbanwe ọkwa glucose ọbara. N'oge usoro ọgwụgwọ na onye nnọchianya a, a na-arụ ọrụ ọfụma na pancreas, nke na - eme ka mmepụta insulin dịkwuo mma.

International Nonproprietary Aha

Glimepiride.

A na-eji mbadamba amaryl mee ihe maka ịgbanwe ọkwa glucose ọbara.

ATX

A10BB12

Ngwakọta

Akụrụngwa na-arụ ọrụ bụ glimepiride. Ihe ndi ozo na ihe mejuputara adighi egosi aru oru hypoglycemic ma eji ha mee ihe iji nweta nchoputa nke ogwu ahu:

lactose monohydrate;
povidone 25000;
stodi sodium carboxymethyl (ụdị A);
steeti magnesium;
microcrystalline cellulose;
anwụ;
indigo carmine (E132).

Usoro onodu ogwu glimepiride na mbadamba 1 nwere ike di iche: 1, 2, 3, 4 mg. Nwere ike ịzụta ngwaahịa a na ngwugwu 30 na 90 PC. Maka ịdị mma nke ịchekwa mbadamba mbadamba, a na-enye blister (pc 15 n'ime nke ọ bụla).

Omume ọgwụ

Amaryl na-ezo aka na ndị na - ahụ ihe hypoglycemic emepụtara maka iji ọnụ. Ọgwụ bụ ihe kachasị enweta na ụdị sulfonylurea. Ngwá ọrụ a bụ ọgbọ ikpeazụ, ya mere enweghị ọtụtụ ọghọm ma e jiri ya tụnyere afọ analogues nke 2 ma ọ bụ 1. Ọgwụ ahụ enweghị mmetụta glucose, mana ọ na - enyere aka iwepụ ihe mgbaàmà nke ọdịnaya dị elu nke ihe a kpatara site na mmekọrịta na mkpụrụ ndụ pancreatic.

Enwere ike ịzụta Amaryl na ngwugwu 30 PC na 90., Maka ịdị mma nke ịchekwa mbadamba, a na-enye blister.

N’okwu a, a na-arụ ọrụ usoro imepụta insulin, n'ihi nke a na-ahazi ọkwa glucose dị n'ọbara. Ọgwụ ọzọ na-enye aka na nghọta nke akwara akụkụ gbasara mmetụta insulin. Na-enye mmụba nke nhaghachi nke anụ ahụ na uto glucose na plasma.

Usoro nke imeputa insulin na ntinye aka nke Amaril sitere na mmechi mmechi uzo potreti nke ATP. N’ihi nke a, a na-emeghe ọwa kalsel. N'ihi nke a, itinye uche nke calcium na sel na-abawanye nke ukwuu. Mmụba na ụba insulin bụ nsonaazụ nke usoro na-aga n’ihu na njikọ nke glimepiride yana protein nke mkpụrụ ndụ beta nke pancreas na mkpo ya.

Amaryl gosiputara ihe ndi ozo: antioxidant, antiplatelet, belata iguzogide insulin. N'ihi nke a, ahụ na-anabata obere usoro nke glimepiride. N'oge ọgwụgwọ, a na - eme ka usoro glucose site na nsị anụ ahụ na - arụ ọrụ, ebe a na - enyefe ihe ahụ n’ime sel akwara na adipocytes (mkpụrụ ndụ adipose).

N'ime ọrịa shuga mellitus nke ụdị nke abụọ, a na-eji nwayọ nwayọ arụ ọrụ a, n'ihi na enwere mmachi na ọsọ nke mmejuputa ya. Glimepiride na-enyere aka mee ka glucose na-arụ ọrụ ngwa ngwa, n'ihi nke ọnọdụ ahụ mmadụ na-eme na hypoglycemia. N'otu oge ahụ, usoro ndị akọwara, enwere mbelata nke mmepụta glucose na umeji.

Ọkara ndụ ọgwụ ọgwụ Amaryl dị n'ahụ ahụ dịruru site na awa ise ruo awa asatọ.

Agbanyeghị, ihe eji eme ihe bụ ihe glimepiride na-emetụta ọrụ nke enzyme cyclooxygenase. N'ihi ya, ike mgbanwe nke arachidonic acid n'ime thromboxane na-ebelata. N'ihi nke a, ọnụego nguzobe nke ọbara ọgbụgba na-agbada, n'ihi na a na-ejigide platelet na mgbidi arịa ọbara. N'otu oge ahụ, a na-achọpụta mbelata nke ume ọfụma na-eme, yana itinye uche ha na-ahazi.

Mlọ ọgwụ

Ọnụego ya maka mkpokọta glimepiride kachasị n'ọbara dabere na oke ọgwụ yana ọdịnaya nke ihe nọ n'ọrụ mejupụtara. A na-etinye obi gị dum n'ọrụ ngwa ngwa ngwa ngwa mgbe enwere ya na afọ na nri. Uru nke ọgwụ a dị oke nkwekọ na protein plasma na bioavailability dị elu (100%).

A na-ewepụpụ akụkụ ahụ nọ n'ọrụ n'oge ụta na mgbe a na-apụ apụ. Ọkara ndụ nke ọgwụ ahụ na-adị site na 5 ruo 8 awa. Ka ị na-anata ụba Amaril, usoro iwepụ ya n’ahụ na-egbu oge. Na-emegide nzụlite nke ọrịa akụrụ na-etolite, ịta nke onye ọrụ a na-ebelata, n'ihi oke nke iwepụ ọkara ndụ ya.

Ihe ngosi maka iji Amaryl mbadamba

Ọgwụ dị irè n'ịgwọ ụdị ọrịa shuga 2, ebe ihe ọghọm nke ịmalitepụta ngosipụta na-adịghị mma na obere nsogbu. A na-eji Amaryl mee ihe dị ka usoro ọgwụgwọ onwe ha ma ọ bụ yana ụzọ ndị ọzọ.

Amaryl na contraindicated na-adịghị ala ala ịhoụ mmanya.

Coma bụ ihe mgbochi megide iji Amaril.

Edeghị Amaryl maka ọrịa shuga mellitus 1.

Ihe ngbanwe

Edeghị ọgwụ a na-a questionụ ọgwụ maka ọnọdụ ọrịa dị otú a:

anabataghị akụkụ ọ bụla, yana ịba ọcha n'anya glimepiride na-etolikarị;
ụdị 1 ọrịa shuga mellitus;
mebiri metabolism, nke a na-esonyere mgbada nke insulin;
Coma, precoma;
a chronicụrụma na-egbu egbu, n'ihi na n'ọnọdụ a, ibu na imeju na-abawanye;
mmeghachi omume na-adịghị mma maka ọgwụ ọ bụla sitere na otu ụdị sulfonylurea.

Jiri nlezianya

Ekwesịrị ịkpachara anya n'ọnọdụ ndị a na-akpata ọrịa nke na-atụ aro ka ị nyefee onye ọrịa ahụ ọgwụ insulin: mmebi nke nnukwu akụkụ nke anụ ahụ n'ihi mkpughe ọkụ, ịwa ahụ, mgbagha nri na ngwa ngwa ị absorụ nri na kemịkal site na mgbidi nke usoro nri.

Etu esi eji ogwu Trulicity?
Ejiri Metformin 1000 nye obere shuga ọbara. Gụkwuo banyere ọgwụ a na ederede.
Ndị dọkịta na-atụ aro iji Metformin Zentiva.

Otu esi ewere mbadamba Amaryl

A na-ewere ọgwụ tupu nri ma ọ bụ jiri nri. A na-ekpebi oge ọgwụgwọ na-adabere na ọnọdụ onye ọrịa, ogo mmepe nke ọrịa ahụ, mana ọtụtụ oge usoro ọgwụgwọ ahụ dị ogologo.

Na-arịa ọrịa shuga

Na mbido ọgwụgwọ, ekwesighi ị moreụ karịa 1 mg. Usoro ọgwụgwọ: a na-ewere mbadamba oge 1 kwa ụbọchị n'ụtụtụ. Ọ bụrụ na achọrọ, a na-abawanye kwa ụbọchị nke ọgwụ ahụ, mana a na-eme ya na nkebi: a na-agbakwunye 1 mg nke ihe ahụ mgbe niile, na ọkwa ikpeazụ - 6 mg. Amachibidoro ya ịgọnarị etu ọgwụ a gosipụtara si dị, n'ihi na ego kachasị ya kwa ụbọchị bụ 6 mg.

A na-ebu Amaryl tupu nri ma ọ bụ jiri nri.

Mmetụta ndị dị n'akụkụ mbadamba Amaryl

Na akụkụ ahụ nke ọhụụ

Ahụhụ ọhụhụ na-ahụgharị ihu n'ihi ntakịrị oge nke oghere nke oghere. N'ihi nke a, akụkụ nke mgbanyụ ọkụ na-agbanwe.

Ọkpụkpụ afọ

Ọgbụgbọ, ọgbụgbọ, mgbu n'ime afọ, ọgba aghara, ọtụtụ ọrịa na - efe efe nke imeju.

Ahụhụ Hematopoietic

Mgbanwe nke ihe ọbara na ihe mejupụtara, dị ka thrombocytopenia.

Site n'akụkụ nke metabolism

Inweta ọgwụ a na-eche mgbe ụfọdụ na-akpatakarị mbelata nke glucose dị ala. N'okwu a, mgbaàmà na-ebilite: isi ọwụwa, ọgbụgbọ, ọgbụgbọ, adịghị ike n'ozuzu, ike iwe na-abawanye, ntị na-agbagha, igwe ojii nke nsụhọ, ịda mba, mgbanwe mgbanwe nke obi, ama ama, ọkwa nke nrụgide na-agbanwe (elu).

Mgbe ha nwesịrị ọgwụ ahụ, ụfọdụ ndị ọrịa tolitere thrombocytopenia.

Mgbe ị usingụ ọgwụ ahụ, ọgbụgbọ na ọgbụgbọ nwere ike ịda.

Na-emegide usoro ọgwụgwọ ọgwụ, ịda mba nwere ike ịmalite.

Otutu mgbe enwere isi ọwụwa, nke bụ akara nke mmetụta dị n'akụkụ.

Ọrịa ọgbụgba bụ mmetụta dị n'akụkụ Amaril.

N'oge ọgwụgwọ na Amaril, a na-achọpụta ihe mgbu nke afọ.

Ahụhụ

Oge a na-eme ugboro ugboro n'oge usoro ọgwụgwọ Amaril bụ urticaria, yana ọnya, itching. N'adịghị ka ọ bụla, ọnọdụ ujo, vasculitis, dyspnea tolitere.

Mmetụta ikike ịchịkwa usoro

Enwere ihe ize ndụ nke hypo- na hyperglycemia, nke nwere ike ibute nlebara anya, mgbanwe na mmụọ, yana mmeghachi omume psychomotor na-akawanye njọ. Ekwesịrị ịkpachara anya mgbe ị na-anya ụgbọala.

Ntụziaka pụrụ iche

Site na njikọta ọgwụgwọ na Metformin, a na-achọpụta ọganihu na njikwa metabolic.

Kama Metformin, enwere ike ịkọ ọgwụ insulin. N'otu oge ahụ, usoro nke ịchịkwa metabolism metabolism dịkwa mfe.

Ọ bụrụ na onye ọrịa ahụ tolitere mmeghachi omume nke mmadụ na ọgwụ a inụrụ ya na nke kacha nta (1 mg), o zuru ezu ịgbaso nri iji kwado ọkwa glucose nkịtị.

Iji ọgwụgwọ a na-achọ nyocha mgbe niile: nyochaa usoro nke imeju na ọbara. Ọrụ dị mkpa na nke a bụ leukocytes na platelet.

Jiri na agadi

A na-enyocha usoro ọgwụgwọ yana usoro a na-ahụ maka ya, n'ihi na mgbe ọ bụla ndị ọrịa nke otu a, ọrụ ezumike adịghị arụ ọrụ.

Oge a na-eme ugboro ugboro n'oge usoro ọgwụgwọ Amaril bụ urticaria, yana ọnya, itching.

N'oge usoro ọgwụgwọ Amaril kwesịrị ịkpachara anya mgbe ị na-anya ụgbọala.

Mgbe ị na-elele Amaril na agadi, a na-enyocha usoro ọgwụgwọ na dose ya.

Nyere na enweghi ozi banyere nchekwa nke Amaril na ọgwụgwọ ndị ọrịa na-erubeghị afọ 18, enweghị ike iji ya.

Inye umuaka

Nyere na enweghi ozi banyere nchekwa nke ọgwụ a na-ekwu na ọgwụgwọ ndị ọrịa na-erubeghị afọ 18, enweghị ike iji ya.

Jiri n'oge ime na lactation

Edeghị Amaryl ụmụ nwanyị oge ị na-azụ nwa na inye ara.

Ngwa maka ọrụ ezughi oke ọrụ

Ejighị ngwá ọrụ ahụ.

Jiri maka ọrụ imeju na-arụ ọrụ

Mmebi ahụ siri ike na akụkụ a bụ ihe a na - egbochi iji Amaril. Ọ bụrụ na imeju akwara bidoro, ihe ọghọm nke nsogbu na-abawanye.

Dodoụbiga ya ókè

Hypoglycemia na-egosipụta. Ihe mgbaàmà nke ọnọdụ a dịgidere ruo ụbọchị 1-3. Nwere ike iwepu ihe mgbaàmà ahụ site na ị aụ ọgwụ carbohydrates. Iji weghachi ọkwa glucose ngwa ngwa, a na-atụ aro ka ị bute ọgbụgbọ ma drinkụọ mmiri dị ukwuu.

An anụbiga ọgwụ ike ókè, onye ọrịa ahụ nwere ihe mgbaàmà nke hypoglycemia.

Ọ bụrụ na arụ ọrụ ezughi oke ọrụ, ejighị Amaryl.

Mbibi imeju bụ ihe megidere iji Amaril.

Edeghị Amaryl ụmụ nwanyị oge ị na-azụ nwa na inye ara.

Mmekọrịta na ọgwụ ndị ọzọ

Enwere ohere nke mbelata glucose ma ọ bụrụ na, ya na Amaril, insulin ma ọ bụ ọgwụ hypoglycemic, Allopurinol, anabolics, Chloramphenicol, ọgwụ nwere ọgwụ homonụ, ndị na-egbochi ACE.

A na-enweta mmetụta dị iche na nchịkọta nke Amaril na barbiturates, GCS, mkpụrụ nke thiazide otu, Epinephrine.

Ọrụ nke ọgwụ coumarin nwere ike ibelata ma mụbaa ma ọ bụrụ na edepụtara ọgwụ ndị a n'otu oge na ọgwụ a na-eme.

Mmanya ndakọrịta

Ọ gaghị ekwe omume ị drinkụ mmanya nwere mmanya n'otu oge ahụ dịka Amaril, n'ihi na nsonaazụ nke ngwakọta nke ihe ndị a bụ ihe a na-enweghị ike ịkọwapụta: mmetụta hypoglycemic nwere ike ịbawanye ike ma mee ka ọ ghara isi ike.