Otu n'ime ọgwụ kachasị mma maka ndị ọrịa shuga n'ihe gbasara ọnụ ahịa yana arụ ọrụ bụ insulin insulin, nke ụlọ ọrụ America bụ Eli Lily na ndị enyemaka ya na mba ndị ọzọ mepụtara. Otutu insulins mepụtara n'okpuru aha ika a nwere otutu ihe. Enwekwara homonụ dị mkpụmkpụ nke ezubere iji belata shuga mgbe ị risịrị nri, yana ọgwụ ọkara oge emebere iji kwado glycemia na-ebu ọnụ.
Enwekwara nkwakọba nke emechara nke insulins abụọ mbụ nke nwere ihe ruru awa 24. Ejirila ụdị Humulin niile na ọgwụgwọ ọrịa shuga ruo ọtụtụ iri afọ, ma na-ekpebi site na nyocha ndị ahụ, a ga-emepụta ha ogologo oge. Ọgwụ ndị a na-enye njikwa glycemic dị mma, na-egosipụta nkwụsi ike na ịkọ ihe.
Pesdị na ụdị nke mwepụta Humulin
Insulin Humulin bụ homonụ nke na-emeghachi insulin na - arụ ọrụ n'ime ahụ mmadụ kpamkpam, nhazi amino acid na ịdị arọ nke molekul. Emeghachiri ya, ya bụ, dịka usoro nke injin si arụ ọrụ. Usoro ogwu a na-agbakọ nke ọma nwere ike weghachite metabolism na ndị nwere ọrịa shuga ma zere nsogbu.
Ọrịa shuga na oke nrụgide ga-abụ ihe mgbe ochie
- Normalization shuga -95%
- Mwepu nke akwara mbufụt - 70%
- Mwepu nke obi ike -90%
- Bibie ọbara mgbali elu - 92%
- Mmụba na ume n'ụbọchị, na-eme ka ụra na-ehi ụra n'abalị -97%
Ulindị Humulin:
- Humulin Regular - Nke a bụ ihe ngwọta nke insulin dị ọcha, na-ezo aka ọgwụ na-eme obere ihe. Ebumnuche ya bụ inyere shuga dị n’ọbara aka ịba n’ime sel, ebe ahụ na-eji ya eme ihe maka ike. A na-ejikarị ya na insulin na-ajụ ma ọ bụ ogologo oge. Enwere ike inye ya naanị ma ọ bụrụ na onye ọrịa nwere ọrịa shuga arụnye insulin insulin.
- Humulin NPH - nkwusioru mere na insulin na protamine sulfate. N'ihi mgbakwunye a, ike iwetulata shuga na-amalite nwayọ nwayọ karịa na insulin mkpụmkpụ, ma na-anọ ogologo oge. Abụọ abụọ na-agba kwa ụbọchị zuru iji mezie glycemia n'etiti nri. Ọtụtụ mgbe, a na-enye Humulin NPH yana insulin mkpụmkpụ, mana ya na ụdị shuga 2 enwere ike iji ya mee onwe ya.
- Humulin M3 - Nke a bụ ọgwụ nwere usoro abụọ nwere 30% insulin insulin na 70% - NPH. A na-ahụkarị na ire ere bụ Humulin M2, o nwere ogo 20:80. N'ihi eziokwu ahụ bụ na onye mere ya wepụtara nha nke hormone ahụ n’ebughi n'uche mkpa onye ọrịa ahụ, enweghị ike ịchịkwa shuga ọbara site na enyemaka ya dịka ọ na - eji insulin dị mkpụmkpụ na nke dị iche. Enwere ike iji Humulin M3 nwere ndị ọrịa shuga, bụ ndị tụrụ aro usoro ọdịnala nke ọgwụ insulin.
Ntuziaka maka oge ime ihe:
Humulin | Oge ihe omume | ||
mbido | kacha | njedebe | |
Mgbe | 0,5 | 1-3 | 5-7 |
NPH | 1 | 2-8 | 18-20 |
M3 na M2 | 0,5 | 1-8,5 | 14-15 |
Niile insulin na-emepụta Humulin nwere ugbu a nwere mkpo U100, yabụ, ọ dị mma maka sirinji insens na nke sirinji ọgbara ọhụrụ.
Mwepụta Mwepụta:
- iko karama na olu nke 10 ml;
- katọn dị iche iche maka mkpịsị mkpụrụ sirinji, nke nwere 3 ml, na ngwugwu nke iberibe 5.
A na-edozi insulin Humulin subcutaneously, n'ọnọdụ ndị kachasị njọ - intramuscularly. A na-anabata nchịkwa intraven naanị maka Humulin Regular, a na-eji ya wepụ hyperglycemia siri ike ma ekwesịrị ịme ya. naanị n'okpuru nlekọta ahụike.
Ihe ngosi na contraindications
Dịka ntuziaka ahụ si dị, enwere ike ịdere ndị ọrịa Humulin niile nwere nnukwu insulin. A na-ahụkarị ya na ndị nwere ọrịa shuga 1 ma ọ bụ karịa afọ 2. Inyocha insulin nwa oge ga-ekwe omume mgbe ị na-ebu nwata, ebe ọ bụ na amachibidoro ọgwụ mmịnye shuga n'oge a.
Edere Humulin M3 naanị maka ndị ọrịa toro eto, maka ndị iji usoro nlekọta insulin na-esiri ike siri ike. N'ihi oke ịba ụba nke ọrịa shuga ruo afọ 18, a naghị atụ aro Humulin M3.
Ohere nwere ike ịpụta:
- Hypoglycemia n'ihi ịba ụba nke insulin, a chọpụtaghị maka mmega ahụ, enweghi carbohydrates na nri.
- Ọrịa nfụkasị ahụ, dịka ihe ọkụ ọkụ, ọzịza, itching, na ịcha ọbara-ọbara n’ebe a na-agba ya. Enwere ike ibute ya site na ma insulin mmadụ na ngwa enyemaka nke ọgwụ. Ọ bụrụ na aria ahụ na-adịgide n'ime otu izu, a ga-eji insulin dochie Humulin na ihe mebere ya.
- Akwara mgbu ma ọ bụ ure, palpitations nwere ike ime mgbe onye ọrịa nwere nnukwu potassium. Ihe mgbaàmà na-apụ n'anya mgbe iwepu ụkọ nke macronutrient a.
- Gbanwee na ọkpụrụkpụ nke anụ ahụ na ọnya subcutaneous na saịtị nke injections ugboro ugboro.
Stokwụsị ịchịkọta insulin n'oge niile na-egbu egbu, yabụ, ọbụlagodi na ahụ erughị ala, a ga-aga n'ihu ịgwọ insulin ruo mgbe gị na dọkịta gị ga-atụle.
Imirikiti ndị ọrịa edepụtara ọgwụ Humulin enweghị nsogbu ọ bụla na-abụghị ọrịa hypoglycemia dị nwayọ.
Humulin - ntuziaka maka ojiji
Ngụkọta ọnya, nkwadebe maka ntụtụ na nchịkwa nke Humulin bụ otu ihe na insulin ndị ọzọ siri nwee otu oge. Nanị ihe dị iche bụ na oge tupu iri nri. Na Humulin Regular ọ dị nkeji iri atọ. Ọ dị mma ịkwadebe maka nhazi nke mbụ nke hormone tupu ị gụọ akwụkwọ ntuziaka maka ojiji.
Nkwadebe
A ga-ewepụ insulin na friji tupu oge eruo ka ọnọdụ okpomọkụ nke ihe ngwọta nwude ya. A ga-akpụgharịrị akpa ma ọ bụ karama nke ngwakọta homonụ nke protamine (Humulin NPH, Humulin M3 na M2) n'etiti nkwụ n'ọtụtụ oge wee tụgharịa wee gbadata ka nkwusiori nke dị na ala gbazee kpamkpam na nkwụchi ahụ ga-enweta otu agba milky na-enweghị ntụgharị. Ikwanye ya n'ike ka i ghara ijikwa okpukpu gabiga ókè nke nkwusioru gi. Humulin oge nile achoghi ime nkwadebe di otu a;
A na-ahọrọ ogologo oge agịga ahụ n'ụzọ ga - eme ka a hụ ntụtụ dị n'okpuru ma ghara ịbanye na akwara. Mpempe sirinji kwesịrị ekwesị maka insulin Humulin - Humapen, BD-Pen na analogues ha.
Okwu mmeghe
A na-etinye insulin n'ime anụ ahụ mepụtara abụba: afọ, apata ụkwụ, ikpere na ogwe aka dị elu. A na-ahụ nnabata kachasị ọsọ na edo edo na ntinye n'ime afọ, ya mere a na-akwụ Humulin Regular ebe ahụ. Iji mee ka ọgwụ ahụ rụọ ọrụ ntuziaka ahụ, ọ gaghị ekwe omume ịbawanye mgbasa ọbara na ebe a na-agbanye: ite, kpuchie, na mikpuo na mmiri ọkụ.
Mgbe ị na-ewebata Humulin, ọ dị mkpa ịghara ịgba ọsọ: jiri nwayọ kpoo mkpokọta akpụkpọ ahụ na-enweghị ijide olu ahụ, jiri nwayọ gbanye ọgwụ ahụ, wee jiri agịga ahụ na akpụkpọ ahụ ruo ọtụtụ sekọnd ka ngwọta ahụ wee ghara ịmalite ịpụ. Iji belata ihe egwu nke lipodystrophy na mbufụt, agịga agịga mgbe ejiri nke ọ bụla.
Ingsdọ aka na ntị
Ekwesịrị ịhọrọ ọgwụ mbụ Humulin yana njikọta na dibia bekee. Dodoụbiga mmanya ókè nwere ike ibute shuga na shuga na hypoglycemic coma. Ezigbo homonụ ahụ ezughi oke na ketoacidosis na-arịa ọrịa shuga, angiopathies na neuropathy dị iche iche.
Dsdị insulin dị iche iche dị iche na arụmọrụ, yabụ ịkwesịrị ịgbanweta na Humulin na ọgwụ ọzọ naanị ma ọ bụrụ na nsonaazụ ya ma ọ bụ ụgwọ ezughi oke maka ọrịa shuga. Ntugharị chọrọ ntụgharị nke dose na mgbakwunye, njikwa glycemic ugboro ugboro.
Mkpa insulin nwere ike ịba ụba n'oge mgbanwe homonụ na ahụ, ebe ị na-a medicationsụ ọgwụ ụfọdụ, ọrịa na-efe efe, nchekasị. Achọrọ obere homonụ maka ndị ọrịa nwere ọrịa ịba ọcha n'anya na, ọkachasị, ọdịda akụrụ.
Dodoụbiga ya ókè
Ọ bụrụ n’inweta insulin karịa ka ọ dị mkpa iji mee ka mmiri ara ehi ndị ahụ riri, onye ọrịa nwere ọrịa shuga ga-enwerịrị ike inwe hypoglycemia. Ọtụtụ mgbe, a na-esonyere ya ịma jijiji, akpata oyi, adịghị ike, agụụ, agụụ, na ịsụsọ na-agba agba. N'ụfọdụ ndị ọrịa mamịrị, a na-ehichapụ ihe mgbaàmà ya, mbelata ụdị shuga dị oke ize ndụ, ebe ọ bụ na enweghị ike igbochi ya na oge. Udiri hypoglycemia ugboro ugboro na neuropathy na-arịa ọrịa mamịrị nwere ike ibute mgbaàmà nke mgbaàmà.
Ozugbo ihe banyere hypoglycemia, a na-akwụsị ya ngwa ngwa site na carbohydrates ngwa ngwa - shuga, ihe ọ fruitụ fruitụ mkpụrụ osisi, mbadamba glucose. Ọgwụ ị excessụbiga ọgwụ ike nwere ike ibute ọrịa hypoglycemia, ruo na mmalite nke Coma. N'ụlọ, enwere ike iwepu ya ngwa ngwa site na ntinye nke glucagon, enwere ngwa pụrụ iche maka nlekọta mberede maka ndị nwere ọrịa shuga, dịka ọmụmaatụ, GlucaGen HypoKit. Ọ bụrụ na ụlọ ahịa glucose dị na imeju dị obere, ọgwụ a agaghị enyere aka. Nanị ọgwụgwọ dị mma na nke a bụ nchịkwa mgbochi ọbara nke glucose n'ụlọ ọgwụ. Ọ dị mkpa ịnapụta onye ọrịa ebe ahụ ozugbo enwere ike, ebe ọ bụ na coma na-akawanye ngwa ngwa ma na-akpatara ahụ mmerụ ahụ na-enweghị atụ.
Iwu nchekwa nchekwa Humulin
Typesdị insulin niile chọrọ ọnọdụ nchekwa pụrụ iche. Njirimara nke homonụ na-agbanwe nke ukwuu n’oge nfụkasị, ekpughere radieshon ultraviolet na okpomọkụ karịa 35 Celsius. A na-echekwa ngwaahịa na friji, n'ọnụ ụzọ ma ọ bụ na shelf tere mgbidi azụ. Ndụ shelf dịka ntuziaka maka ojiji: afọ 3 maka Humulin NPH na M3, afọ 2 maka Rekpụrụ. Kalama a na-emeghe nwere ike ịdị na okpomọkụ nke 15-25 Celsius C maka ụbọchị 28.
Mmetụta ọgwụ na humulin
Ọgwụ nwere ike igbanwe nsonaazụ insulin ma bulie ohere nke nsonaazụ. Ya mere, mgbe ị na-edepụta homonụ, dọkịta ga-enyerịrị ndepụta zuru oke nke ọgwụ were, gụnyere ọgwụ mkpuru, vitamin, nri nri, mgbakwunye egwuregwu na ọgwụ mgbochi.
Ihe a nwere ike isi na ya pụta:
Mmetụta n'ahụ | Ndepụta ọgwụ |
Mmụba na shuga, ịba ụba na dose insulin chọrọ. | Ihe mgbochi oral, glucocorticoids, androgens sịntetik, homonụ thyroid, ụrọ β2-adrenergic ahọrọ, gụnyere terbutaline na salbutamol. Ọgwụ ịgba maka ụkwara nta, nicotinic acid, ịkwado lithium. Thiazide diuretics ji wee gwọọ ọbara mgbali elu. |
Mbelata shuga. Iji zere hypoglycemia, a ga-ebelata ọgwụ Humulin ga-ebelata. | Tetracyclines, salicylates, sulfonamides, anabolics, beta-blockers, ndị na-ahụ maka hypoglycemic maka ịgwọ ụdị ọrịa shuga 2. A na - ejikarị ndị na - egbochi ACE (dịka enalapril) na ndị na - anabata ihe na AT1 (losartan) na - agwọ ọrịa ọbara mgbali elu. |
Mmetụta ndị a na-enweghị ike ịkọ nkọ na glucose ọbara. | Mmanya na-egbu egbu, pentacarinate, clonidine. |
Mbelata ihe mgbaàmà nke hypoglycemia, ọ bụ ya mere o ji esi ike iwepụ ya na oge. | Ndị na-egbochi Beta, dịka ọmụmaatụ, metoprolol, propranolol, ụfọdụ anya na-ada maka ọgwụgwọ nke glaucoma. |
Njirimara nke iji mee n’oge ime
Iji zere mmebi nke nwa ebu n'afọ n'oge afọ ime, ọ dị mkpa ijigide mmekpa ahụ nkịtị. Amachibidoro ọgwụ hypoglycemic n'oge a, ebe ha na-egbochi inye ụmụaka nri. Nanị ọgwụgwọ ga-ekwe n'oge a bụ insulin ogologo ma dị mkpụmkpụ, gụnyere Humulin NPH na Regular. Ntughari Humulin M3 adighi nma, ebe o nweghi ike imegwara onye obia shuga nke oma.
N'oge afọ ime, mkpa nke homonụ na-agbanwe ọtụtụ oge: ọ na-agbada n'ime ọnwa atọ, na-abawanye nke ukwuu n'ime afọ 2 na nke 3, ma na-agbadata ozugbo ozugbo ịmụ nwa. Ya mere, ndị dọkịta niile na-eduzi afọ ime na ịmụ nwa kwesịrị ịgwa ndị ọnụnọ shuga n'ime ụmụ nwanyị.
Analogs
Kedu ihe nwere ike dochie anya insulin Humulin ma ọ bụrụ na mmetụta ndị ọ ga-apụta:
Ọgwụ | Ọnụ ego maka 1 ml, ite. | Analogue | Ọnụ ego maka 1 ml, ite. | ||
kalama | ngwungwu pen | kalama | katriki | ||
Humulin NPH | 17 | 23 | Biosulin N | 53 | 73 |
Insuman Bazal GT | 66 | - | |||
Rinsulin NPH | 44 | 103 | |||
Protafan NM | 41 | 60 | |||
Humulin Regular | 17 | 24 | Actrapid NM | 39 | 53 |
Rinsulin P | 44 | 89 | |||
Insuman Rapid GT | 63 | - | |||
Biosulin P | 49 | 71 | |||
Humulin M3 | 17 | 23 | Mikstard 30 nm | Ugbu a adịghị | |
Gensulin M30 |
Tebụl a depụtara naanị analogues zuru oke - insulins mmadụ mepụtara site na ogologo oge.